Protein Alignment alpha-Est9 and Ces1b

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001074841.1
• Gene: Ces1b / 382044
• MGIID: 3779470
• Length: 567
• Species: Mus musculus
• Alignment Length: 558
• Identity: 167/558 - (29%)
• Similarity: 241/558 - (43%)
• Gaps: 111/558 - (19%)

  Fly    33 VVSTTYGPIKGVKRKSIYGQSYFSFER-------IPFAKPPVGELRYKAPQPPEVWTEVRSCTSQ 90
            ||.||.|.|.| |..|:.|     ||.       :||||||:|.||:..|:|.|.|:.|::.||.
Mouse    25 VVDTTQGKILG-KYTSLEG-----FEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATSY 83

  Fly    91 GPKPLQKHFVFEMTDG-------------SEDCLYLNVYT-KNLYPTKPMPVMVWIYGGGFQFGE 141
            .|...|.....::...             ||||||||:|: .:|..:..:||||||:|||...|.
Mouse    84 PPMCSQDAVAVQLLSDMLSTKKESIPPLFSEDCLYLNIYSPADLTKSSLLPVMVWIHGGGLMTGG 148

  Fly   142 ASRECYSPDYL-LREDVVVISINYRLGPLG---TNDDTWKKKHIFNISLPGFLCLDDPELDVPGN 202
            ||  .|:...| ..|:|||::|.||||..|   |.|:..:                       ||
Mouse   149 AS--LYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSR-----------------------GN 188

  Fly   203 AGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGNTLSP 267
            ....||:.|||||:.|.:.|||:..::|:||.|||..||..::::.....|||:||..|...|..
Mouse   189 WAHLDQLAALRWVQDNIANFGGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLEN 253

  Fly   268 WAVTPQR---NWPYRLAVQAGYAGENNTRDVW--------EFLKNAKGSEIIKANGELCIDEEKK 321
            ..:|...   :....:|..:|....::|..|.        |.|:.....|:.|..|..   ..||
Mouse   254 IVITLDLVACDLSQMIATVSGCNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAA---SAKK 315

  Fly   322 ERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNE-GLL-------LYSETKT 378
            :....|       .|....|:||.|.|::.....:.:|.|:|....| |.:       |.||.|.
Mouse   316 DNTSMS-------TVIDGVVLPKAPEEILAEKSFSTVPYIVGFNKQEFGWIIPTMLGDLLSEGKM 373

  Fly   379 NPKCLNELDDCRFVVPIELNMDRESALCREYGDQLRQCYYGDKTPSLDTLHEYLQMVSHEYFWFP 443
            |.:..:.|.. ||...:.::.....|:..:|   ||..  .|.....|.|   |.|.|..:|..|
Mouse   374 NEETASLLLR-RFHSDLNISESLIPAVIEKY---LRGT--DDPAKKRDLL---LDMFSDVFFGIP 429

  Fly   444 IYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTCHGDDLSYLFYNSLARKLKNH 508
              ..:|||........||:|.|.:.....:..|    .:.|.|. |||::..:|...|   ||..
Mouse   430 --AVLLSRSLRDAGVSTYMYEFRYRPSFVSDKR----PQTVEGD-HGDEIFSVFGIPL---LKEG 484

  Fly   509 TREYKC-IERLV-GLWTHFAACGNPNFD-----PEQED 539
            |.|.:. :.::| ..|.:||..||||.:     ||.::
Mouse   485 TSEEETNLSKMVMKFWANFARNGNPNGEGLPHWPEYDE 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	167/558 (30%)
		Aes	<115..>237	CDD:223730	45/126 (36%)
Ces1b	NP_001074841.1	COesterase	19..547	CDD:278561	167/558 (30%)
		Aes	<121..>239	CDD:223730	49/142 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832609
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740