Protein Alignment alpha-Est9 and Nceh1

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_848887.1
• Gene: Nceh1 / 320024
• MGIID: 2443191
• Length: 408
• Species: Mus musculus
• Alignment Length: 296
• Identity: 63/296 - (21%)
• Similarity: 112/296 - (37%)
• Gaps: 85/296 - (28%)

  Fly    88 TSQGPKPLQKHFVFEMTDGSEDCLYLNVYTKNLYPTKPM-PVMVWIYGGGFQFGEASRECYSPDY 151
            ||.|.:..:.....::||...|.:.:.|:..:..|.:|: ..:::|:|||:....|....|  |.
Mouse    67 TSFGKQSARSSPKVKVTDTDFDGVEVRVFEGSPKPEEPLRRSVIYIHGGGWALASAKISYY--DQ 129

  Fly   152 L---LREDV--VVISINYRLGPLGTNDDTWKKKHIFNI--SLPGFL---CLDDPELDVPGNAGLK 206
            |   :.|::  |::||.|||.|     ..:..:.|.::  :...||   .||..::| ||..|:
Mouse   130 LCTTMAEELNAVIVSIEYRLVP-----QVYFPEQIHDVIRATKYFLQPEVLDKYKVD-PGRVGI- 187

  Fly   207 DQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAIC------------ 259
                            .||||.    |:.|.:....:..:....:.|..:|:.
Mouse   188 ----------------SGDSAG----GNLAAALGQQFTYVASLKNKLKLQALVYPVLQALDFNTP 232

  Fly   260 ---MSGNT-LSP-------WAVTPQRNWPYRLAVQAGYAGENNTRDV-----------WEFL--- 299
               .|.|| :.|       |....:.|:.:   |:|.....:.:.||           |..|
Mouse   233 SYQQSMNTPILPRHVMVRYWLDYFKGNYDF---VEAMIVNNHTSLDVERAAALRARLDWTSLLPS 294

  Fly   300 ---KNAKGSEIIKANGELCIDEEKKERIGFSFGPVI 332
               ||.|  .|::..|...|.:|..:.:..:..|:|
Mouse   295 SIKKNYK--PIMQTTGNARIVQEIPQLLDAAASPLI 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	63/296 (21%)
Nceh1	NP_848887.1	Abhydrolase_3	109..381	CDD:400284	54/254 (21%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	113..115		0/1 (0%)