Protein Alignment alpha-Est9 and Nceh1

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001120996.1
• Gene: Nceh1 / 294930
• RGDID: 1311104
• Length: 408
• Species: Rattus norvegicus
• Alignment Length: 334
• Identity: 71/334 - (21%)
• Similarity: 115/334 - (34%)
• Gaps: 102/334 - (30%)

  Fly    89 SQGPKPLQKHFVFEMTDGSEDCLYLNVYTKNLYPTKPM-PVMVWIYGGGFQFGEASRECYSPDYL 152
            |.|.|..:.....::||...|.:.:.|:.....|.:|: ..:|:|:|||:....|....|  |.|
  Rat    68 SFGKKSARSSPRVKVTDTDFDGVEVRVFEGPPKPDEPLRRSVVYIHGGGWALASAKISYY--DQL 130

  Fly   153 ---LREDV--VVISINYRLGPLGTNDDTWKKKHIFNI--SLPGFL---CLDDPELDVPGNAGLKD 207
               :.|::  |::||.|||.|     ..:..:.|.::  :...||   .||..::| ||..|:
  Rat   131 CTAMAEELNAVIVSIEYRLVP-----QVYFPEQIHDVIRATKYFLQPEVLDKYKVD-PGRVGV-- 187

  Fly   208 QVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGNTLSPWAVTP 272
                           .||||.    |:.|.:....:..:....:.|..:|:      :.|.....
  Rat   188 ---------------SGDSAG----GNLAAALGQQFTYVESLKNKLKLQAL------IYPVLQAL 227

  Fly   273 QRNWPYRLAVQAGYAGENNT----RDV----W-EFLK-NAKGSEIIKANGELCIDEEKKERIGFS 327
            ..|.|       .|....||    |.|    | ::.| |....|.:..|....:|.|:...:
  Rat   228 DFNTP-------SYQQSMNTPILPRHVMVRYWVDYFKGNYDFVEAMIVNNHTSLDVERAAAL--- 282

  Fly   328 FGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGLLLYSETKTNPK-CLNELDDCRF 391
                                 ..|..|::.:|              |..|.|.| .|..:.|.|.
  Rat   283 ---------------------RARLDWTSLLP--------------SSIKKNYKPVLQTIGDARI 312

  Fly   392 VVPIELNMD 400
            |..|...:|
  Rat   313 VKEIPQLLD 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	71/334 (21%)
Nceh1	NP_001120996.1	Abhydrolase_3	109..381	CDD:400284	62/293 (21%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	113..115		0/1 (0%)