Protein Alignment alpha-Est9 and Nlgn3

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_766520.2
• Gene: Nlgn3 / 245537
• MGIID: 2444609
• Length: 825
• Species: Mus musculus
• Alignment Length: 635
• Identity: 161/635 - (25%)
• Similarity: 262/635 - (41%)
• Gaps: 163/635 - (25%)

  Fly    34 VSTTYGPIKGVK---RKSIYG--QSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGPK 93
            |:|.:|.::|.:   ...|.|  ..|..   :|:|.||:||.|:..|:||..|:.:|:.|...|.
Mouse    41 VNTHFGKLRGARVPLPSEILGPVDQYLG---VPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPV 102

  Fly    94 -PLQKHFVFE------------------MTDGSEDCLYLNVYT---------------------- 117
             |...|....                  :.:.:|||||||||.
Mouse   103 CPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDE 167

  Fly   118 -KNLYPTKPMPVMVWIYGGGFQFGEASR------ECYSPDYLLREDVVVISINYRLGPLGTNDDT 175
             :::..:...||||:|:||.:..|..:.      ..|.       :|:||::|||:|.|
Mouse   168 DEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYG-------NVIVITLNYRVGVL------ 219

  Fly   176 WKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSAS 240
                        |||...|..  ..||.||.||:.|||||..|.:.||||...||:||...|::.
Mouse   220 ------------GFLSTGDQA--AKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASC 270

  Fly   241 VHYMMITEQTHGLFHKAICMSGNTLSPWAVTPQRNWPYR-LAVQAGYAGEN--NTRDVWEFLKNA 302
            |..:.::..:.|||.:||..||:.||.|||..|   |.: .::.|...|.|  :|.|:.:.|:..
Mouse   271 VSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQ---PVKYTSLLADKVGCNVLDTVDMVDCLRQK 332

  Fly   303 KGSEIIKANGELCIDEEKKERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSN 367
            ...|:::       .:.:..|...:|||||:     ..|:|..|..:|......|..:::|....
Mouse   333 SAKELVE-------QDIQPARYHVAFGPVID-----GDVIPDDPEILMEQGEFLNYDIMLGVNQG 385

  Fly   368 EGLLLYSETKTNPKCLNELDDCRFVVPIELNMDRESALCREYG-----DQLRQC---YYGD--KT 422
            || |.:.|...:|:  :.:....|...:...:|      ..||     |.||:.   .|.|  ..
Mouse   386 EG-LKFVEGVVDPE--DGVSGTDFDYSVSNFVD------NLYGYPEGKDTLRETIKFMYTDWADR 441

  Fly   423 PSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYAR-SAPTYLYRFDFDSKHFNHLRILSCGKKVR- 485
            .:.:|..:.|..:..::.|  :..:|::...:|| .:|||.|.|      ::|     |...::
Mouse   442 DNPETRRKTLVALFTDHQW--VEPSVVTADLHARYGSPTYFYAF------YHH-----CQSLMKP 493

  Fly   486 ---GTCHGDDLSYLFYNSLARKLK----NHTREYKCIERLV-GLWTHFAACGNPNFDPEQED--- 539
               ...|||::.|:|...:.....    |.::....:..:| ..||:||..|:|| .|..:|
Mouse   494 AWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-KPVPQDTKF 557

  Fly   540 -----------LWQPVDPAAVEKHQLKCLNISDELKVIDVPDLKKLMVWE 578
                       .|...:|    :.|| .|:|..:.:|.|.....|:..|:
Mouse   558 IHTKANRFEEVAWSKYNP----RDQL-YLHIGLKPRVRDHYRATKVAFWK 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	154/610 (25%)
		Aes	<115..>237	CDD:223730	43/150 (29%)
Nlgn3	NP_766520.2	COesterase	39..601	CDD:365897	160/632 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..172		0/20 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..668

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832448
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740