Protein Alignment alpha-Est9 and NLGN1

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001352852.1
• Gene: NLGN1 / 22871
• HGNCID: 14291
• Length: 843
• Species: Homo sapiens
• Alignment Length: 645
• Identity: 165/645 - (25%)
• Similarity: 257/645 - (39%)
• Gaps: 185/645 - (28%)

  Fly    33 VVSTTYGPIKGVKRK---SIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGPKP 94
            :|:|.:|.|:|:|::   .|.| ....|..:|:|.||.||.|::.|:||..|:::|:.|...|..
Human    54 LVATNFGKIRGIKKELNNEILG-PVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVC 117

  Fly    95 LQKHFVFE----------------------MTDGSEDCLYLNVYTKNLYPTK------------- 124
            .|.  :.:                      :.|.||||||||:|.    ||:
Human   118 PQN--IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYV----PTEDGPLTKKQTDDLG 176

  Fly   125 ---------------PMPVMVWIYGGGFQFGEASRECYSPDYLLR-EDVVVISINYRLGPLGTND 173
                           |.||||:|:||.:.  |.:...|....|.. .:|:||::|||||.|
Human   177 DNDGAEDEDIRDSGGPKPVMVYIHGGSYM--EGTGNLYDGSVLASYGNVIVITVNYRLGVL---- 235

  Fly   174 DTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGS 238
                          |||...|..  ..||.||.|.:.||||...|...||||...||:||..||.
Human   236 --------------GFLSTGDQA--AKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGG 284

  Fly   239 ASVHYMMI---------TEQTHGLFHKAICMSGNTLSPWAVTPQ-RNWPYRLAVQAGYAGENNTR 293
            :.|:.:.:         :..|.|||.:||..||..||.|||:.| ..:...||.:.| ...::|.
Human   285 SCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVG-CNVSDTV 348

  Fly   294 DVWEFLKNAKGSEIIKANGELCIDEE-KKERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNN 357
            ::.|.|:.....|:        :|:: :..|...:|||||:     ..|:|..|..:|......|
Human   349 ELVECLQKKPYKEL--------VDQDIQPARYHIAFGPVID-----GDVIPDDPQILMEQGEFLN 400

  Fly   358 IPLIIGGVSNEGLLLYSETKTNPKCLNELDDCRFVVPIELNMDRESALCREYG-----DQLRQC- 416
            ..:::|....|||....         |.:|....:...:.:....:.:...||     |.||:.
Human   401 YDIMLGVNQGEGLKFVE---------NIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETI 456

  Fly   417 --YYGD----KTPSLDTLHEYLQMVSHEYFWF-PIYRTVLSRLQYARSAPTYLYRFDFDSKHFNH 474
              .|.|    ..|  :|..:.|..:..::.|. |...|  :.|.....:|||.|.|      ::|
Human   457 KFMYTDWADRHNP--ETRRKTLLALFTDHQWVAPAVAT--ADLHSNFGSPTYFYAF------YHH 511

  Fly   475 LRILSCGKKV---RGTCHGDDLSYLFYNSLARKLKNHTREYKC--------IERLV-GLWTHFAA 527
            .:.    .:|   ....|||::.|:    |...:...|..:.|        :..:| ..||:||.
Human   512 CQT----DQVPAWADAAHGDEVPYV----LGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAK 568

  Fly   528 CGNPNFDPEQEDLWQPVDPAAVEKHQLKCLNISDELKVIDV-PDLKKLMVWESFFRRDEL 586
            .|:||         |||               ..:.|.|.. |:..:.:.|..:.::|:|
Human   569 TGDPN---------QPV---------------PQDTKFIHTKPNRFEEVAWTRYSQKDQL 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	159/611 (26%)
		Aes	<115..>237	CDD:223730	45/150 (30%)
NLGN1	NP_001352852.1	COesterase	53..626	CDD:365897	165/645 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142651
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740