Protein Alignment alpha-Est9 and Nlgn1

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_006535478.1
• Gene: Nlgn1 / 192167
• MGIID: 2179435
• Length: 863
• Species: Mus musculus
• Alignment Length: 664
• Identity: 167/664 - (25%)
• Similarity: 255/664 - (38%)
• Gaps: 203/664 - (30%)

  Fly    33 VVSTTYGPIKGVKRK---SIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGPKP 94
            :|:|.:|.|:|:|::   .|.| ....|..:|:|.||.||.|::.|:||..|:::|:.|...|..
Mouse    54 LVTTNFGKIRGIKKELNNEILG-PVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVC 117

  Fly    95 LQKHFVFE----------------------MTDGSEDCLYLNVYTKNLYPTK------------- 124
            .|.  :.:                      :.|.||||||||:|.    ||:
Mouse   118 PQN--IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYV----PTEDVKRISKECARKP 176

  Fly   125 -----------------------------------PMPVMVWIYGGGFQFGEASRECYSPDYLLR 154
                                               |.||||:|:||.:.  |.:...|....|..
Mouse   177 GKKICRKGGPLTKKHTDDLGDNDGAEDEDIRDSGGPKPVMVYIHGGSYM--EGTGNLYDGSVLAS 239

  Fly   155 -EDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKAN 218
             .:|:||::|||||.|                  |||...|..  ..||.||.|.:.||||...|
Mouse   240 YGNVIVITVNYRLGVL------------------GFLSTGDQA--AKGNYGLLDLIQALRWTSEN 284

  Fly   219 CSRFGGDSANITIFGDSAGSASVHYMMI---------TEQTHGLFHKAICMSGNTLSPWAVTPQ- 273
            ...||||...||:||..||.:.|:.:.:         :..|.|||.:||..||..||.|||:.|
Mouse   285 IGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQP 349

  Fly   274 RNWPYRLAVQAGYAGENNTRDVWEFLKNAKGSEIIKANGELCIDEEKKERIGFSFGPVIEPYVTS 338
            ..:...||.:.| ...::|.::.|.|:.       |...||...:.:..|...:|||||:
Mouse   350 AKYARILATKVG-CNVSDTVELVECLQK-------KPYKELVDQDVQPARYHIAFGPVID----- 401

  Fly   339 HCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGLLLYSETKTNPKCLNELDDCRFVVPIELNMDRES 403
            ..|:|..|..:|......|..:::|....|||....         |.:|....|...:.:....:
Mouse   402 GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVE---------NIVDSDDGVSASDFDFAVSN 457

  Fly   404 ALCREYG-----DQLRQC---YYGD----KTPSLDTLHEYLQMVSHEYFWF-PIYRTVLSRLQYA 455
            .:...||     |.||:.   .|.|    ..|  :|..:.|..:..::.|. |...|  :.|...
Mouse   458 FVDNLYGYPEGKDVLRETIKFMYTDWADRHNP--ETRRKTLLALFTDHQWVAPAVAT--ADLHSN 518

  Fly   456 RSAPTYLYRFDFDSKHFNHLRILSCGKKV---RGTCHGDDLSYLFYNSLARKLKNHTREYKC--- 514
            ..:|||.|.|      ::|.:.    .:|   ....|||::.|:    |...:...|..:.|
Mouse   519 FGSPTYFYAF------YHHCQT----DQVPAWADAAHGDEVPYV----LGIPMIGPTELFPCNFS 569

  Fly   515 -----IERLV-GLWTHFAACGNPNFDPEQEDLWQPVDPAAVEKHQLKCLNISDELKVIDV-PDLK 572
                 :..:| ..||:||..|:||         |||               ..:.|.|.. |:..
Mouse   570 KNDVMLSAVVMTYWTNFAKTGDPN---------QPV---------------PQDTKFIHTKPNRF 610

  Fly   573 KLMVWESFFRRDEL 586
            :.:.|..:.::|:|
Mouse   611 EEVAWTRYSQKDQL 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	161/630 (26%)
		Aes	<115..>237	CDD:223730	45/170 (26%)
Nlgn1	XP_006535478.1	COesterase	53..646	CDD:365897	167/664 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832533
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740