Protein Alignment alpha-Est9 and cest-7

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001257187.1
• Gene: cest-7 / 182819
• WormBaseID: WBGene00007693
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 611
• Identity: 135/611 - (22%)
• Similarity: 221/611 - (36%)
• Gaps: 192/611 - (31%)

  Fly     9 QFK-----------IGLKMVDFKVQQRRYRTSEKTVVSTTYGPIKGVKRKSIYGQSYFSFERIPF 62
            |||           :.|.:..||            |::|.||.::|:...|......:.|:.|||
 Worm    16 QFKKMKIFFYTLALLALSVKSFK------------VLNTNYGKVRGITDFSDKRNHKYIFKGIPF 68

  Fly    63 AKPPVGELRYKAPQPPEVWTEV-------RSCTSQGP-KPLQKHFVFEMTDGSEDCLYLNVYTKN 119
            ||||:|.||:..|:.|..|..|       .:|.|... ...|:..:      ||||||:|::|..
 Worm    69 AKPPLGLLRFALPEEPNTWNGVLDGSKYSAACLSNSSLASAQQENI------SEDCLYINIFTSE 127

  Fly   120 LYPTKPMPVMVWIYGGGFQFGEASRECYSPDYLLREDVV----VISI-NYRLGPLGTNDDTWKKK 179
            .......||:|:.:||.|....|:   ..||..:.|..|    |.:| .||||..|.
 Worm   128 YCLAHKCPVLVYYHGGSFNLDSAT---MFPDKFILERYVDSGIVFAIPAYRLGVFGQ-------- 181

  Fly   180 HIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYM 244
              |.:...|.         ||.|..:.|.:.:|.:|..|.:.||||...:|:.|.|:|...|:.|
 Worm   182 --FYLGEQGI---------VPANLLIHDCIRSLNFVHDNIASFGGDPNYVTLMGHSSGGQLVNAM 235

  Fly   245 MITEQ---THGLFHKAICMS------------GNTLSPWAVTPQRNWPYRLAVQAGYAGENNTRD 294
            ..:.|   ...||.:.|.:|            ||:             |.:|.:.....| |:::
 Worm   236 GFSNQIDPEKKLFQQFIVLSSIGMYGFEDLQIGNS-------------YEIARRHNCTSE-NSQE 286

  Fly   295 VWEFLKNAKGSEIIKANGELCIDEEKKERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIP 359
            :.:.::|....::::.  :..:|:...    ..|..:|.       ..|...::...:.:..|:
 Worm   287 IVDCMRNIDALQLLQT--QTVMDDVDL----LFFKAIIR-------APPLMDVKQKLSEFKENV- 337

  Fly   360 LIIGGVSNEGLLLYSETKTNPKCLNELDDCRFVVPIELNMDRESALCREYGDQLRQCYYGDKT-- 422
                            |..|..|  .:.|..|.:             .:|.|.    ||...|
 Worm   338 ----------------TARNMLC--GVTDNEFTI-------------FKYPDG----YYISATFL 367

  Fly   423 ---PSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYA--RSAPTY----------LYRFDFDSKHF 472
               ..:||::.|....::      |..|.::....|  .||.||          :|.|:...|.|
 Worm   368 DFENPVDTVNVYRNKFTN------ITPTFVNSDSSAVFVSAATYSEALTNAGGNVYLFESRQKPF 426

  Fly   473 NHLRILSCGKKVRGTCHGDDLSYLFYNSLARKLKNHTREYKCIERLVG-LWTHFAACGNPNFDPE 536
                          :.|..|:.|  :..:.|: ||||.:...::.... |..:|...|:|:  |.
 Worm   427 --------------SMHVTDMQY--FIGIHRE-KNHTTDMDILDSFYSKLLVNFTKFGSPS--PN 472

  Fly   537 QEDLWQPVDPAAVEKHQLKCLNISDE 562
                |:..||:   |.....:.|..|
 Worm   473 ----WEKYDPS---KMNFMAMEIDTE 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	129/577 (22%)
cest-7	NP_001257187.1	alpha/beta hydrolases	38..510	CDD:473884	130/589 (22%)