Protein Alignment alpha-Est9 and cest-8

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001359583.1
• Gene: cest-8 / 182818
• WormBaseID: WBGene00007691
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 124/584 - (21%)
• Similarity: 211/584 - (36%)
• Gaps: 178/584 - (30%)

  Fly    26 YRTSEKTVVSTTYGPIKGVKRKSIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEV------ 84
            |......:::|:||.::|:...|......|:|:.:||||||:|.||:..||..:.|..:
 Worm    13 YEFQTLKIINTSYGKLRGMAEWSDDANHKFTFKSVPFAKPPIGNLRFAPPQKLDHWDGILDASVY 77

  Fly    85 -RSCTSQGPKPLQKHFVFEMTDGSEDCLYLNVYTKNLYPTKPMPVMVWIYGGGFQFGEASRECYS 148
             .:|.|......|.:.       :|||||:|::|..........|:|:.:||.:....|:  .:|
 Worm    78 SAACMSNSTLTTQSYV-------NEDCLYINIFTSEKCLKSKCSVIVYFHGGAYNTESAT--MFS 133

  Fly   149 PDYLL----REDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQV 209
            ..::|    .|||:.:....|||..|        :..|.           |...:..|..:.|.:
 Worm   134 DRFILDRYVHEDVIFVIPAVRLGVFG--------QLYFG-----------PNAYLTENLFMFDAI 179

  Fly   210 LALRWVKANCSRFGGDSANITIFGDSAGSASVH---YMMITEQTHGLFHKAICMSGNTL------ 265
            |||.:|....|.||||...:||.|.|:|...|.   :..:.:....||.:.|.:|...:
 Worm   180 LALDFVHNEISNFGGDPEKVTIMGHSSGGTLVEALGFSSMVDPELKLFQQMIMLSSTGMFGFDDL 244

  Fly   266 ---SPWAVTPQRNWPYRLAVQAGYAGENNTRDVWEFL---KNAKGSEIIKANGELCIDEEKKERI 324
               :.:.:..      :|....|...|.||.:|.|.|   ::..|.||::...::    |..:::
 Worm   245 VIDNSFTIVE------KLGCFNGTKEERNTVNVAETLDCMRHIDGYEILRVQQKM----ELMDQL 299

  Fly   325 GFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGLLLYSETKTNPKCLNELDDC 389
            .|.:                    ::|.|   ...|:.|.:::      .:..|:|
 Worm   300 SFKY--------------------LLRGA---PFMLLNGNIAD------LKKNTSP--------- 326

  Fly   390 RFVVPIELNMDRESALCREYGDQLRQCYYGDKTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQY 454
                                    |...:|      .|.||:.. |:.:|    :|.|| :.|.|
 Worm   327 ------------------------RNAIFG------TTEHEFFD-VTEKY----LYITV-TFLDY 355

  Fly   455 ARSAPTYLYRFDFDSKHFNHLRILSCGKKV-----RGTC----------------------HGDD 492
            ..  |..:.| ::|.:...::..:..|...     ..||                      |..|
 Worm   356 EN--PVAVAR-NYDGRLMKNMETMITGDSAAIFVSTATCAAAMANAGADVFLFETRQSYSVHVSD 417

  Fly   493 LSYLFYNSLARKLKNHTREYKCIERLVG-LWTHFAACGNPNFDPEQEDLWQPVDPAAVEKHQLK 555
            :.|...|..|.   |.|.:...::.... |.|:|...|.|:  |.    |.||||..:...:||
 Worm   418 MQYFIGNHCAH---NRTIDIDILDSFYSKLLTNFTKHGKPS--PG----WDPVDPGRMNYLELK 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	123/578 (21%)
cest-8	NP_001359583.1	alpha/beta hydrolases	19..495	CDD:473884	123/578 (21%)