Protein Alignment alpha-Est9 and cest-9.1

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001359584.1
• Gene: cest-9.1 / 181383
• WormBaseID: WBGene00007692
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 134/590 - (22%)
• Similarity: 229/590 - (38%)
• Gaps: 156/590 - (26%)

  Fly    33 VVSTTYGPIKGVKRKSIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGPKPL-- 95
            |:.|:||.::|:...|......:.|:.:||||||||.||:..||.||.|:.:...:...|..:
 Worm    20 VIQTSYGKLRGITVWSNDKNHRYMFKSVPFAKPPVGNLRFAKPQNPESWSGILDASKYSPACMSN 84

  Fly    96 -------QKHFVFEMTDGSEDCLYLNVYTKNLYPTKPMPVMVWIYGGGFQFGEA--SRECYSPDY 151
                   |||:       ||||||:|::|.........||:|:.:||.:....|  ..:.:..|.
 Worm    85 SSSTSTPQKHY-------SEDCLYINIFTSEKCLNSKCPVIVYFHGGAYNLDSAIMFNDTFILDR 142

  Fly   152 LLREDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVK 216
            ...||||.:....|||..|.                  |.....:| :..|..|.|.|.||.:|.
 Worm   143 YAAEDVVFVIPAVRLGVFGQ------------------LYFGPSDL-LSENLFLYDAVQALSFVH 188

  Fly   217 ANCSRFGGDSANITIFGDSAGSASVH---YMMITEQTHGLFHKAICMSGNTLSPWAVTPQRNWPY 278
            :..:.|||||..:|..|.|:|...|.   :..:.:....||.:.|.:|...:..:         |
 Worm   189 SEINYFGGDSKRVTAMGHSSGGTIVDALGFSKLIDPGVKLFQQMIVLSATGMFGF---------Y 244

  Fly   279 RLAVQAGYA------GENNTRD---------VWEFLKNAKGSEIIKANGELCIDEEKKERIGFSF 328
            .:.|...:|      ..|.|:|         :.:.::...|.|::.....:   ||..:|   .|
 Worm   245 DMVVDNSFAIVEKFGCYNGTKDDRPNANIAEMLDCMRQIDGREMLLMQRHM---EEVDDR---DF 303

  Fly   329 GPVIE--PYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGLLLYSETKTNPKCLNELDDCRF 391
            ..|:.  |::.|:    .|..::.::..|.|             |||..|:...:.::.::.  :
 Worm   304 RSVLRGAPFLESN----GKIADLKKSPPSRN-------------LLYGTTEHEFRNVDHMNP--Y 349

  Fly   392 VVPIELNMDRESALCREYGDQLRQCYYGDKTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYAR 456
            :..|.|:.|...|:.|.|.:||        ..:|:|      |::.:.....|..:..|......
 Worm   350 ISGIFLDFDNPVAVARYYDEQL--------MANLET------MINGDAAAIFICASTFSTAMANT 400

  Fly   457 SAPTYLYR-----FDF---DSKHFNHLRILSCGKKVRGTCHGDDLSYL--FYNSLARKLKNHTRE 511
            .|..||:.     :.|   |.::|..:.        |...|..|:..|  ||:.|.
 Worm   401 GADVYLFETRQKPYSFHVSDMQYFVGIH--------REIYHRPDMDILDTFYSKLL--------- 448

  Fly   512 YKCIERLVGLWTHFAACGNPNFDPEQEDLWQPVDPAAVEKHQLKCLNISDELK----VIDVPDLK 572
                       .:|...|.|:  ||    |.|:||..:...:||   :..::|    :::....|
 Worm   449 -----------VNFTKMGVPS--PE----WAPLDPERMNYLELK---VDSDMKEGPVMLEGFHEK 493

  Fly   573 KLMVW 577
            ::.:|
 Worm   494 EMELW 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	133/588 (23%)
cest-9.1	NP_001359584.1	alpha/beta hydrolases	19..484	CDD:473884	132/574 (23%)