Protein Alignment alpha-Est9 and cest-19

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_509187.4
• Gene: cest-19 / 180973
• WormBaseID: WBGene00020125
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 620
• Identity: 167/620 - (26%)
• Similarity: 249/620 - (40%)
• Gaps: 174/620 - (28%)

  Fly    39 GPIKGVKRKSIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGPKPLQKHFVFEM 103
            |.|:| :|....||.|..|:.||||.||||.||::.|:.|..|..|.:.|......:|.  :.|.
 Worm    33 GAIRG-ERLLTDGQDYSVFKGIPFAMPPVGYLRFQMPKEPAKWRGVMNATQYSAMCMQN--IDEN 94

  Fly   104 TDG---------SEDCLYLNVY--TKNLYPTKPMPVMVWIYGGGFQFGEAS---RECYSPDYLLR 154
            ..|         |||||||||:  |...|.....||:|:|:||.||.|..|   :.....:::.|
 Worm    95 DAGEPERYVAHVSEDCLYLNVFSPTPYQYTNDTYPVIVFIHGGRFQTGSGSDIPQRAILSNFVSR 159

  Fly   155 EDVVVISINYRLGPLG---TNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVK 216
            : :|.::.||||||||   |.|..                       :|||.||.||:.||:|||
 Worm   160 K-IVFVTFNYRLGPLGFASTGDSV-----------------------LPGNIGLWDQIWALKWVK 200

  Fly   217 ANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGNTLSPWAV-TPQRNWPYRL 280
            ||...||||.:||.:.|...|:||...:.::.:..|||.|.:.|||:.|.|..| ..|.|..:.:
 Worm   201 ANAEVFGGDPSNILLMGHGTGAASASLLALSPRAEGLFQKVLLMSGSALQPGVVRNTQVNATWNM 265

  Fly   281 AVQAGYAGENNTRDVWEFLKNAKGSEIIKANGELCIDEEKKE------RIGF----SFGPVIEPY 335
            ..:.|....|:             ||::.     |..:..||      |:.|    .|.|:|:..
 Worm   266 NDRFGCRAFNS-------------SELLD-----CARKRSKEEIFQYKRLHFDDYEEFVPIIDGV 312

  Fly   336 VTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEG---LLLYSETKTNPKCLNELDDCRFVVPIEL 397
               ..::|:.|.::  |......|::||...:|.   :||          |||.|         |
 Worm   313 ---GGILPEPPEQL--TLHRRKTPIVIGTTKDESSLRILL----------LNEKD---------L 353

  Fly   398 NMDRESALCREYGDQL--------------RQCYYGDKT-----------PSLDTLHEYLQMVSH 437
            |.   |::..|.|:.|              |....|.|:           |.....:..|:|.||
 Worm   354 NF---SSITWENGETLADNLTLGFKQFQNHRLISQGCKSEYVWTQVDPSFPESVLFNSLLKMYSH 415

  Fly   438 EYFWFPIYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTCHGDDLSYL------ 496
              ||:....:.|:........|.|||.||..|::|         ..:....||.|..::
 Worm   416 --FWYDAPASQLATYYLKHDLPVYLYSFDHISENF---------YDIDRAFHGVDKLHIFNVTPR 469

  Fly   497 FYNSLARKLKNHTREYKCIERLVGLWTHFAACGNPNFDPEQEDL-WQPVDPAAVEKHQLKCLNIS 560
            |.|.  ||..|...:.:.:|....|..:||..|.|..:.:.... |     .:....:|..|:|:
 Worm   470 FLNK--RKDMNWQLDQRVVEIFSELVANFALYGTPTHENDGFSFNW-----TSTTAKELSYLSIT 527

  Fly   561 D---------------------ELKVIDVPDLKKL 574
            |                     .|..:||.:::::
 Worm   528 DSPSMQVGYRWQGHVFWNWYARSLDAVDVGNIQRI 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	167/620 (27%)
cest-19	NP_509187.4	alpha/beta hydrolases	24..544	CDD:473884	164/600 (27%)