Protein Alignment alpha-Est9 and cest-2.3

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_506510.2
• Gene: cest-2.3 / 179918
• WormBaseID: WBGene00013873
• Length: 665
• Species: Caenorhabditis elegans
• Alignment Length: 583
• Identity: 133/583 - (22%)
• Similarity: 220/583 - (37%)
• Gaps: 179/583 - (30%)

  Fly    28 TSEKTVVSTTYGPIKGVKRKSIYG-QSYFSFERIPFAKPPVGELRYKAPQPPEVWTEV------- 84
            |.|..:::.||.|         :| |:...|..||:.:||:||||::.|:..:.|..|
 Worm    26 TIEGKILNATYSP---------FGNQTATVFLGIPYVEPPIGELRFRKPRLLKSWEGVLETKDYK 81

  Fly    85 RSCTSQGPKPLQKHFVFEMTDGSEDCLYLNVYTKNLY--PTKPMPVMVWIYGGGF--QFGEASRE 145
            .:|.|...|..:..||.|:   ||||||.||:| |.|  ..|...||:.::||..  :.|.|
 Worm    82 PACMSYWRKTFKNGFVGEI---SEDCLYANVFT-NQYCLQNKNCSVMIVVHGGRLVCESGSA--- 139

  Fly   146 CYSPDYLLR------EDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPG--- 201
             :.|:..:.      .::||::.|||||..|..        :||                 |
 Worm   140 -FKPEIFINNFVGQDRNIVVVTFNYRLGVFGFG--------VFN-----------------GETG 178

  Fly   202 --NAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSG-- 262
              |..:.|.:.|::||:....:|||:...||:.|.|||:..:.....:..:.||.|:.|.||.
 Worm   179 DTNVAMYDMLEAVKWVRKEIDQFGGNKDRITMAGHSAGAGLIVDFTSSTLSKGLLHQQIVMSAPL 243

  Fly   263 NTLSPWAVTPQRNWPYRLAVQAGYAGENNTRDVWEFLKNAKGSEIIKAN-GELCIDEEKKERIGF 326
            ..:|..|                               |.||..|:..| |  ||.:|      :
 Worm   244 QDISKSA-------------------------------NFKGMTIVAQNVG--CIPKE------Y 269

  Fly   327 SFGPVIEPYV--TSHCVVPKKPIEMMRTAWS--NNIPLIIGG--VSNEGLLLYSETKTNPKCL-- 383
            .|..:.:..:  |..|:..|...:::....|  .|.....|.  |..:.:..|.:...|...:
 Worm   270 GFRKLSKTQINKTYLCLQNKSAQDLLHAQLSMQQNSTFYFGSPRVDGDFITDYPDNLFNFNTIYP 334

  Fly   384 ---------NELDDCRFVVPIELNMDRESAL---CREYGDQL--------RQC--YYGDKTPSLD 426
                     .||.|..::...:.:..:|..|   |...|.:|        ::|  ||.:.|.:
 Worm   335 INTFIGTTTGELRDSLYITDPKNDRIKEQLLKNMCEHVGYELFEKPEEFTKKCGNYYKNGTDA-- 397

  Fly   427 TLHEYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTC--- 488
                  |.:|.:..::.....|.:..:.|.| ..::|.:|:               |..||.
 Worm   398 ------QFLSDDMEFYSGAIKVANAHKRANS-KVFMYSYDY---------------KGAGTAFHK 440

  Fly   489 --------HGDDLSYLFYNSLARKLKNHTREYKCIERLV-GLWTHFAACGNPNFDPEQEDLWQ 542
                    |.:||.|.|..|....:   .::| .|||:. |:..:|....:|:  |.:...|:
 Worm   441 YLEAPSPHHSEDLIYTFGTSRGPFV---AKDY-VIERIYSGMLANFINFEDPS--PSKTQQWR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	131/579 (23%)
cest-2.3	NP_506510.2	alpha/beta hydrolases	17..532	CDD:473884	133/583 (23%)