Protein Alignment alpha-Est9 and cest-2.1

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 616
• Identity: 134/616 - (21%)
• Similarity: 221/616 - (35%)
• Gaps: 226/616 - (36%)

  Fly    28 TSEKTVVSTTYGPIKGVKRKSIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEV-------R 85
            |.|..::::||.|:.        ..:...|..|||.:||.|.||::.|:||..|..:       .
 Worm    27 TIEGKILTSTYSPLG--------NHTGIGFLGIPFVEPPAGNLRFRKPRPPIPWDGILETKEYKP 83

  Fly    86 SCTSQGPKPLQKHFVFEMTDG-----SEDCLYLNVYTKNLY--PTKPMPVMVWIYGGGFQFGEAS 143
            :|.|...|..:        :|     ||||||.||:| |.|  ..|...||:.::||......||
 Worm    84 ACMSDAKKTYK--------NGVGGPISEDCLYANVFT-NQYCMKRKNCSVMIVVHGGRILTESAS 139

  Fly   144 RECYSPDYLLR------EDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGN 202
              .::|:.|:.      .::||::.|||||..                  ||..|:..:.|  .|
 Worm   140 --AFNPEILVNNFVGQGRNIVVVTFNYRLGTF------------------GFGVLNGEKGD--SN 182

  Fly   203 AGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGNTLSP 267
            .|:.|.:.|::|.:.....|||:...:|:.|.|||.:.|.....:..:.|:.::.|.|||..
 Worm   183 VGMFDMLEAVKWTRKEVHNFGGNKDKLTMVGHSAGGSLVGAFTSSPLSKGMLNQQIIMSGAL--- 244

  Fly   268 WAVTPQRNWPYRLAVQAGYAGENNTR-------DVWEF--------------LKNAKGSEIIKAN 311
                      |::...|.:.|.....       :|:.|              |:|....|::.|
 Worm   245 ----------YQMGKLANFKGMTAMAQKAGCLPEVFGFRKLSQVRIDKTYSCLRNISAQEVLDA- 298

  Fly   312 GELCIDEEKKERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGLLLYSE- 375
             :|.:                                :..|.:..::|.|.|    |.||.||:
 Worm   299 -QLWV--------------------------------LQNTTYYISVPHIDG----EFLLNYSDE 326

  Fly   376 ---------------TKT----NPKCLNELDDCRFVVPIELNMDRESA----LCREYGDQL---- 413
                           |.|    :|..:|:|.          |.|::..    ||...|.:|
 Worm   327 ILASGTIHPINSMIGTTTAELRDPIYINDLK----------NADKKEELLKNLCEHIGYELYTEP 381

  Fly   414 ----RQC--YYG---DKTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFDFDS 469
                |:|  :||   |.....|.:..|...:.            ::....:::...::|.:|:
 Worm   382 EEFSRKCQKFYGNGDDAQFLADDMEFYDGSIK------------VANAHASKNTKVFMYSYDY-- 432

  Fly   470 KHFNHLRILSCGKKVRGTC-----------HGDDLSYLFYNSLARKLKNHTREYKCIERLV-GLW 522
                         |..|..           |.:||.|:|..|..    |.|.:...||::. |::
 Worm   433 -------------KDAGPAFKKYAQAPPPHHSEDLIYVFGTSRG----NFTEKDYVIEQIYSGMF 480

  Fly   523 THFAACGNPNFDPEQEDLWQPVDPAAVEKHQ 553
            ..|...|||:  |.:|..|:...|   ||.:
 Worm   481 ADFVNFGNPS--PSKEQKWKEYSP---EKRE 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	132/611 (22%)
		Aes	<115..>237	CDD:223730	35/129 (27%)
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	134/616 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157079
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740