Protein Alignment alpha-Est9 and cest-1.2

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 613
• Identity: 150/613 - (24%)
• Similarity: 249/613 - (40%)
• Gaps: 164/613 - (26%)

  Fly    25 RYRTSEKTVVSTTYGPIKGVKRKSIY----GQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEV- 84
            ::..|.|..:||  |.|:|.:..|.|    .||..:|..||:.:||:|:||::.|:|.:.|:.|
 Worm    14 QFAISTKVQLST--GIIEGKQLNSTYSPFGNQSAIAFLGIPYVEPPIGDLRFRKPRPQKTWSGVL 76

  Fly    85 ------RSCTSQGPKPLQKHFVFEMTDG--SEDCLYLNVYTKNLY--PTKPMPVMVWIYGGGFQF 139
                  .:|.|...|..:...:    .|  |||||||||.| |.|  ..|...|::.::|||:.|
 Worm    77 ETKKFKPACMSNSTKTYKNGGI----GGPISEDCLYLNVLT-NQYCLENKNCSVVIIVHGGGYLF 136

  Fly   140 GEASRECYSPDYLLR------EDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELD 198
            ..|:  .::.:.|:.      .::||::||||||             ||     ||..|:..|.|
 Worm   137 ESAA--TFNHEILVNNFVGQDRNIVVVTINYRLG-------------IF-----GFGHLNGFEGD 181

  Fly   199 VPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGN 263
              .|.|:.|.:.|::||:....:|||:...||:.|.|||:..|....|:..|.||.|:.|.|||
 Worm   182 --KNVGIFDTLEAVKWVRREIKQFGGNKDRITLAGHSAGAGVVAAFTISPLTKGLIHQQIVMSG- 243

  Fly   264 TLSPWAVTPQRNWPYRLAVQAGYAG---------------------ENNTRDVWEFLKNAKGSEI 307
                    |..|    ::.::.:.|                     |:....|:..|:.....|:
 Worm   244 --------PMTN----MSKKSNFKGMTAMAERVGCHSKKYGFNKLPEHEVEQVYSCLRKKPAQEL 296

  Fly   308 IKANGELCIDEEKKERIGFSFG--PVIEPYVTSH--CVVPKKPIEMMRTAWSNNIPLI--IGGVS 366
            :.|...|.      :...|.||  ||...::|.:  .:..:|.|..:.|........:  .|.:|
 Worm   297 LDAQLWLL------QNSTFYFGAPPVDGEFITDYPDNLYSEKSIFSINTLLGTTTRELQDTGYIS 355

  Fly   367 NEGLLLYSETKTNPKCLNELDDCRFVVPIELNMDRESALCREYGDQLRQCYY-GDKTPSL-DTLH 429
            |..   ||:.:|....|..|.|   .:.||:..:.|     ::..:.::.|. |..:.|| |.:.
 Worm   356 NSN---YSKFETKETFLKNLCD---QIGIEIYKESE-----DFSSKCQKWYINGSDSKSLSDDME 409

  Fly   430 EYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFDFDS-----KHFNHLRILSCGKKVRGTCH 489
            .|.|.::            |:.....:....|:|.:.:..     |.:         .||:...|
 Worm   410 FYTQAIN------------LADAHARKGKKVYMYSYAYSGAGPAFKKY---------MKVKSPHH 453

  Fly   490 GDDLSYLFYNSLARKL---KNHTREYKCIERLVGLWTHFAACGNPNFDPEQEDLWQPVDPAAVEK 551
            .:||.|.|  ...|.:   |::..||    ...|::..|....:|:  |..:..|
 Worm   454 SEDLIYTF--GTHRGVFAPKDYVIEY----IYSGMFADFINFEDPS--PSTDQPW---------- 500

  Fly   552 HQLKCLNISDELKVID------VPDLKK 573
              |:....:.|..::|      :|.:||
 Worm   501 --LQYTKENKEYFLVDFDQNLTMPGMKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	142/579 (25%)
		Aes	<115..>237	CDD:223730	40/129 (31%)
cest-1.2	NP_506504.2	COesterase	21..536	CDD:278561	148/606 (24%)
		Aes	<125..>250	CDD:223730	49/159 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157062
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.830