Protein Alignment alpha-Est9 and cest-33

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_504621.1
• Gene: cest-33 / 179020
• WormBaseID: WBGene00017431
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 165/599 - (27%)
• Similarity: 248/599 - (41%)
• Gaps: 172/599 - (28%)

  Fly    28 TSEKTV--VSTTYGPIKG--VKRKSIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCT 88
            |.|:.|  :..:.||::|  .|...:....|..   ||:|||||||||:|.|...:||||::.|.
 Worm     9 TPEQNVEALKASCGPVRGNIYKHDDVIVDGYLG---IPYAKPPVGELRFKKPVTVDVWTEIKDCY 70

  Fly    89 SQGPKPLQKHFVFEMTDGSED-------------CLYLNVYT--------KNLYPTKPMPVMVWI 132
            ..||..:|       |.|.|.             ||.|||:|        ||     ..||||:|
 Worm    71 KYGPACVQ-------TGGFEQIAGPRTPTPEEAGCLTLNVFTPRNASSEFKN-----GRPVMVYI 123

  Fly   133 YGGGFQFGEASRECYSPDY--------LLREDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGF 189
            :|||::.      |.|.|:        |..:||||:|||||||             :|     ||
 Worm   124 HGGGYEL------CASSDFCAYSLSGTLPLKDVVVVSINYRLG-------------VF-----GF 164

  Fly   190 LCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLF 254
            |...|..  .|||.||.||.|||:||:.:.|.||||...:|:||.|||.||...:.::..:..||
 Worm   165 LTTGDNV--CPGNFGLWDQTLALKWVQKHISSFGGDPNCVTVFGQSAGGASTDLLSLSPHSRDLF 227

  Fly   255 HKAICMSGNTLSPWAVTPQRNWP--YR-LAVQAGYAG-ENNTRDVW------EFLKNAKGSEIIK 309
            .:.|.:||.....:|:....|..  :| .|...|::| :::....|      |.|.|.||
 Worm   228 QRFIPISGTAHCDFAIRASENQAKIFREFAEFHGFSGRDSSALFKWYQEQSPETLSNVKG----- 287

  Fly   310 ANGELCIDEEKKERIGF-SFGPVIE----PYVTSHCVVPKKPIEMMRTAWSNNIP---LIIGGVS 366
                     .||...|| :|.|.::    |          ||::.:|    ...|   ::.|...
 Worm   288 ---------YKKSISGFLTFIPNLDGDFFP----------KPLDELR----KEAPKKQMMTGVTE 329

  Fly   367 NEGLLLYSETKTNPKCLNELDDCRFVVPIELNMDRESALCREYG-------DQLRQCYYG----- 419
            .|||:|.|   .|| ..:..|....::|..:           ||       |::::.:|.
 Worm   330 YEGLMLAS---MNP-AFSPADVGLTLMPQGI-----------YGKDVVSNPDEIQKIFYEKYVEG 379

  Fly   420 -DKTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYARSA-----PTYLYRFDFDSKHFNHLRIL 478
             ||:..|....:..:.:..|:|...:       :|.|::|     ..|.|.|::.:..
 Worm   380 VDKSDELAMRKKLCEALGDEFFNVGV-------IQAAKNAAKHGNEVYFYTFEYVNPD------- 430

  Fly   479 SCG-----KKVRGTCHGDDLSYLFYNSLARKLKNHTREYKCIERLVGLWTHFAACGNPNFDPEQE 538
            |.|     ...:...|..:|.||....:..|.:....:.|.:|....|:::||..||||......
 Worm   431 SFGMWDGMMPFKAAVHCTELRYLLGEGVYSKFEPTEEDRKVMETTTTLFSNFAKYGNPNGKGATA 495

  Fly   539 DLWQPVDPAAVEKH 552
            ::|:.......|:|
 Worm   496 EIWEKYSLNRPERH 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	163/595 (27%)
cest-33	NP_504621.1	Esterase_lipase	16..521	CDD:238191	162/592 (27%)