Protein Alignment alpha-Est9 and cest-35.2

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 154/535 - (28%)
• Similarity: 236/535 - (44%)
• Gaps: 101/535 - (18%)

  Fly    33 VVSTTYGPIKGVKRKSIY--GQSYFS-FERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGP-- 92
            |.:.:.|||:|    ::|  |....: :..|||||.|:|:||:|.....|.||:...|...||
 Worm    16 VFNASCGPIRG----NVYEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYKYGPGC 76

  Fly    93 ---KPLQKHFVFEMT--DGSED-CLYLNVYT---KNLYPTKPMPVMVWIYGGGFQFGEASRECYS 148
               ..|....|.:.|  |.:|| ||.|||:.   |:.......||||:.|||||:.|.:|   ..
 Worm    77 PQSAALGALMVSQATNHDFAEDNCLNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVGFSS---MF 138

  Fly   149 PDYLLR-----EDVVVISINYRLGPLG---TNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGL 205
            .||.|.     :||::::.|||:||||   |.||..:                       ||.||
 Worm   139 DDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDVAR-----------------------GNWGL 180

  Fly   206 KDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGNTLSPWAV 270
            .||.|||:||:.:...||||.:|:||.|.|||.|||.::.::...:..|.|.|.|||....|:.:
 Worm   181 WDQALALQWVQKHIKSFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGI 245

  Fly   271 TPQ--RNWPYR-LAVQAGYAGENNTRDVWEFLKNAKGSEIIKANGELCIDEEKKERIGFSFGPVI 332
            ..:  ....:| .|...||.| |:::.:.::.::......:||.|..|.....     |||.|..
 Worm   246 RSKDVEGLIFREFANHHGYTG-NDSKSLLQWYQSQDSEIFLKAEGYKCPASGM-----FSFVPNF 304

  Fly   333 E----PYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGL---LLYSETKTNPKCLNELDDCR 390
            :    |          ||.:.:|.. :..:..|:.....|||   ..|:..||..:.|:.
 Worm   305 DGDFFP----------KPFDELRKE-APKLGAIVSIGEYEGLGFEDFYAGQKTPQQMLSA----- 353

  Fly   391 FVVPIELNMDRESALCREYGDQLRQCYYGDKTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYA 455
             .:..|:..:||..:.|.....|:.   |......:.....:::....||....:.||.|.::|.
 Worm   354 -ALGPEVVRNREEVVKRAAESYLKN---GGNENEENIAKTLVEIFGDYYFSVGAFDTVRSLVKYG 414

  Fly   456 RSAPTYLYRFDFDSKHFNHLRILSCGKK--VRGTCHGDDLSYLFYNSLARKLKNHTREYKCIERL 518
            .:  .|||.|::    ||....:..||.  .....||.||.|:|.....    ..::|.:.:..:
 Worm   415 NT--VYLYSFNY----FNPNTPIVFGKNRPFNAANHGSDLRYIFGEGTG----EFSKEDRQVMDM 469

  Fly   519 VGLW-THFAACGNPN 532
            :|.: |:||..||||
 Worm   470 MGTYHTNFAKYGNPN 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	154/535 (29%)
		Aes	<115..>237	CDD:223730	48/132 (36%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	154/535 (29%)
		Aes	<105..>239	CDD:223730	59/159 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157293
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740