Protein Alignment alpha-Est9 and cest-6

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_501070.1
• Gene: cest-6 / 177459
• WormBaseID: WBGene00020688
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 566
• Identity: 136/566 - (24%)
• Similarity: 218/566 - (38%)
• Gaps: 145/566 - (25%)

  Fly     4 MAAFDQFKIGLKMVDFKVQQRRYRTSEKTVVSTTYGPIKGVKRKSIYGQ--SYFSFERIPFAKPP 66
            |..||.....|.:|     ...|::.|..|::|:.|.|.|       .|  ||.:|::|||||||
 Worm     1 MGNFDMLIFVLLIV-----YSAYKSCEAGVITTSLGSING-------NQIGSYQTFKKIPFAKPP 53

  Fly    67 VGELRYKAPQPPEVWTEVRSCTSQGP---------KPLQKHFVFEMTDGSEDCLYLNVYTKN-LY 121
            :|:||::.|...|.|..:.:.|..||         |..||..       .||||::|::|.: ..
 Worm    54 IGKLRFQKPMAAEKWEGILNATEYGPACMSNSSTSKSPQKWI-------DEDCLHINIFTTDTCL 111

  Fly   122 PTKPMPVMVWIYGGGFQFGEA--SRECYSPDYLLREDVVVISINYRLGPLGTNDDTWKKKHIFNI 184
            .:|...|:.:::||...:..|  ..:.|..|.....||:::...:|||
 Worm   112 SSKNCSVVFYVHGGELVYDSAVMFEDKYLFDTFSSRDVILVIPAFRLG----------------- 159

  Fly   185 SLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQ 249
             |.....::|..: .|.|..|.|.:|||.:||:....|||.|..:|.||.|.|...|..|..:.:
 Worm   160 -LFSHFVVEDQNV-APNNLALYDILLALEFVKSEIHNFGGSSDRVTAFGHSYGGHVVSVMAFSTE 222

  Fly   250 TH---GLFHKAICMSGNTLSPWAVTPQRNWPYRLAVQAGYAGENNTRDVWEFLKNAKGSEIIK-- 309
            .:   ..|.:.||||                              :.:||:.|:    .||.|
 Worm   223 INTDLSYFQRVICMS------------------------------SVNVWDSLE----FEIEKTM 253

  Fly   310 -----ANGELC-IDEEKKERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWS---NNIPLIIGGV 365
                 ||   | :.::.|.|: .||..  :.|: ..|:.....:|::|...|   ...|:..|.|
 Worm   254 RFIQYAN---CSVPQDLKSRM-TSFEQ--DSYM-MECLQDIDSMELLRIQRSLEDEGHPIYSGLV 311

  Fly   366 SNEGLL---LYSETKTNPKCLNELDDCRFVVPIELNMDRESA---LCREYG-DQLRQC---YYGD 420
            ..|.|:   |..:....||.:..|..|.:     ..:|:..|   :....| :..::|   |..|
 Worm   312 LREPLIQNVLVQDFYEKPKNIPTLTGCTY-----KELDKFHAYHNIVETLGYENYKECDDKYRDD 371

  Fly   421 KTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVR 485
            :......|:::    :.|.|.......:....|..:..|||.|.:.: .||
 Worm   372 RKYGRFDLNKH----ADETFGILAQTKLKVDKQLDKGIPTYFYEYSY-PKH-------------- 417

  Fly   486 GTCHGDDLSYLFYNSLARKLKNHTREYKCIERLVGLWTHFAACGNP 531
             ..|.|||||:.......|.:|.....|..:.   ::.:|...|.|
 Worm   418 -PSHTDDLSYIMGVHAFEKDENEIHLAKSYQE---MFMNFVKFGEP 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	129/537 (24%)
		Aes	<115..>237	CDD:223730	32/124 (26%)
cest-6	NP_501070.1	Abhydrolase	25..500	CDD:389770	129/537 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156949
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.830