Protein Alignment alpha-Est9 and cest-4

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_501043.1
• Gene: cest-4 / 177445
• WormBaseID: WBGene00015930
• Length: 592
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 143/573 - (24%)
• Similarity: 236/573 - (41%)
• Gaps: 144/573 - (25%)

  Fly    26 YRTSEKTVVSTTYGPIKGVKRKSIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQ 90
            :..::..:|||:.|.|.|.:    .| |:..|:.||.||||:|:||::.|:|||.||.||:..:.
 Worm    21 FSITKSAIVSTSLGQIDGDQ----IG-SFHLFKHIPLAKPPIGKLRFQKPEPPEKWTGVRNAKAY 80

  Fly    91 GPKPLQKHFVFEMTDG--SEDCLYLNVYTKN-LYPTKPMPVMVWIYGGGFQFGEASRECYSPDYL 152
            ||..:....|......  .||||::|::|.: ...:|...|:.:.:|||..:..|  ..::..||
 Worm    81 GPACISNSSVSTSPQKWIDEDCLHINIFTSDKCLKSKDCAVVTYFHGGGLMYDSA--VMFNDTYL 143

  Fly   153 L----REDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALR 213
            |    .:||::....:|||             ||:     ...::|..: .|.|..|.|.:|.:.
 Worm   144 LGTFVNQDVIIAIPAFRLG-------------IFS-----HFVVEDQSI-APTNLALYDILLGVE 189

  Fly   214 WVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTH---GLFHKAICM-SGNTLSPWAVTPQR 274
            :||.....|||::...||.|.|.|.:.|:.:..:.:.:   .||.::||| ||:......:..|:
 Worm   190 FVKNEIHNFGGNNQKNTIMGHSYGGSIVNILTFSSKINHDLSLFQQSICMSSGHDFETLEIQIQK 254

  Fly   275 NWPYRLAVQAG------YAGENNTR--DVWEF--LKNAKGSEIIKANGELCIDEEKKERIGFSFG 329
            .  .|.|..||      ...:..||  |::..  |:|....|:::....|   |:
 Worm   255 T--NRFAKHAGCTVPSIIEKKMTTRQSDLYRMKCLQNKDALELLRVQRLL---ED---------- 304

  Fly   330 PVIEPYVTSHCVVPKKPI-------EMMRTAWSNNIPLIIGGVSNEGLLLYSETKTNPKCLNELD 387
               |.|.|...:|.::|:       |.|::  ...||::.|....|     .:....||.:.:.
 Worm   305 ---EGYPTYGYLVQREPLIQEIPYQEFMKS--PKKIPMLTGCTRYE-----MDHSPAPKPIGQA- 358

  Fly   388 DCRFVVPIELNM------DRESALCREYGDQLRQCYYGDKTPSLDTLHEYLQMVSHEYFWFPIYR 446
             ..|..|.|:.|      |.|   ..|:|:      :.|:|.::        ||.        .|
 Worm   359 -LGFENPEEVYMKFRKDWDDE---VYEFGN------HSDETQAI--------MVQ--------VR 397

  Fly   447 TVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTCHGDDLSYLFYNSLARKLKNHTRE 511
            ..::.| .:::.|.|||.:.:.    .|.|            |.|||.||.......|.:|....
 Worm   398 VRVNNL-LSKNVPAYLYEYTYP----KHAR------------HTDDLFYLMGVHRFEKDENEIEL 445

  Fly   512 YKCIERLVGLWTHFAACGNP-------NFDPEQ--EDLWQPVDPAAVEKHQLK 555
            .|..|.   ::.:||..|:|       |.:.|.  |..|   |....|:.|:|
 Worm   446 GKVYET---IFMNFAKFGDPKEGFELANAENESYYEVYW---DGETGERPQMK 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	142/564 (25%)
		Aes	<115..>237	CDD:223730	32/126 (25%)
cest-4	NP_501043.1	Abhydrolase	28..503	CDD:389770	143/566 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900