Protein Alignment alpha-Est9 and cest-5.1

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 130/548 - (23%)
• Similarity: 215/548 - (39%)
• Gaps: 138/548 - (25%)

  Fly    29 SEKTVVSTTYGPIKGVKRKSIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGP- 92
            ::..::.|::|.::|.:    .| .|..|::|||||||||.||::.|:....|..:||....||
 Worm    16 ADSLIIHTSFGHLEGAE----IG-DYHLFKKIPFAKPPVGNLRFQKPEAAGKWDGIRSAIEYGPA 75

  Fly    93 --------KPLQKHFVFEMTDGSEDCLYLNVYT-KNLYPTKPMPVMVWIYGGGFQFGEA--SREC 146
                    |..||..       .||||::|::| |....::...:.|:|:|||..:..|  ..:.
 Worm    76 CMSNSSKTKSPQKWV-------DEDCLHVNIFTSKKCLKSRNCAIAVYIHGGGLTYDSAVMFNDT 133

  Fly   147 YSPDYLLREDVVVISINYRLGPLGTNDDTWKKKHIF--------NISLPGFLCLDDPELDVPGNA 203
            ...|..::.||:::...:|||             ||        |::              |.|.
 Worm   134 VLLDTFVKRDVILVIPGFRLG-------------IFSHFTVHNQNVA--------------PNNL 171

  Fly   204 GLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTH---GLFHKAICMSG--- 262
            .|.|..|||.:||:....|||:|..||:||.|.|......|..:.:.:   .||.:||.|||
 Worm   172 ALYDITLALEFVKSEIHSFGGNSQKITLFGHSYGGGLASMMTFSSEINRDLSLFQQAIVMSGGFY 236

  Fly   263 -NTLSPWAVTPQR-----NWPYRLAVQAGYAGENNTRDVWEFLKNAKGSEIIKANGELCIDEEKK 321
             ..|.......:|     |....|.::...........:.:.|:...|.|:::....|   |:|
 Worm   237 FEELKDHIEGTKRFVEYANCSVPLKLERKMERSQQEMYMMKCLQKLSGMELLRIQRLL---EDK- 297

  Fly   322 ERIGF-SFGPVI--EPYVTSHCVVPK-KPIEMMRTAWSNNIPLIIGGVSNEGLLLYSETKTNPKC 382
               |: .||.||  ||      :.|. |..|::::  ..|||::.|                  |
 Worm   298 ---GYPDFGGVILREP------LFPDVKKFELLKS--PKNIPMLTG------------------C 333

  Fly   383 LN-ELDDCRFVVPIELNMDRESALCREYGDQLRQCYYGDKTPSLDTLHEYLQMVSHEYFWFPIYR 446
            .| |.|.....||....::.|:.      |:..:.|..|....::....:....  :....|:..
 Worm   334 TNLEFDHESIKVPFGKYLEFENP------DECDEKYRNDVESGVENRGNHTDKT--QGIILPLKL 390

  Fly   447 TVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTCHGDDLSYLFYNSLARKLKNHTRE 511
            .:.:.|:  .:...|||.:.: .||         |:      |.|||||:.......|.:|....
 Worm   391 QINNLLE--NNVTAYLYEYTY-PKH---------GR------HTDDLSYIMGVHAFEKDENEVHL 437

  Fly   512 YKCIERLVGLWTHFAACGNPNFDPEQED 539
            .:..:.:|   .:|...|.|....|:.:
 Worm   438 EQVYKDMV---INFIKLGEPGMGFEKSE 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	130/545 (24%)
cest-5.1	NP_501022.3	alpha/beta hydrolases	17..495	CDD:473884	130/547 (24%)