Protein Alignment alpha-Est9 and Ces1e

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_598421.1
• Gene: Ces1e / 13897
• MGIID: 95432
• Length: 562
• Species: Mus musculus
• Alignment Length: 622
• Identity: 167/622 - (26%)
• Similarity: 260/622 - (41%)
• Gaps: 152/622 - (24%)

  Fly    29 SEKTVVSTTYGPIKGVKRKSIYG--QSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQG 91
            |...:|.|..|.:.| |..|:.|  |....|..:||||||:|.||:..|||.|.|:.|::.||..
Mouse    22 SSPPMVDTVQGKVLG-KYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSSVKNATSYP 85

  Fly    92 P----KPLQKHFVFEMTDG---------SEDCLYLNVYT-KNLYPTKPMPVMVWIYGGGFQFGEA 142
            |    .|:....|.::...         ||||||||:|| .:|..:..:||||||:|||...|.|
Mouse    86 PMCFQDPVTGQIVNDLLTNRKEKIPLQFSEDCLYLNIYTPADLTKSDRLPVMVWIHGGGLVLGGA 150

  Fly   143 SRECYSPDYLL---REDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAG 204
            |    :.|.|:   .|:|||:.|.||||       .|           ||....|..  ..||.|
Mouse   151 S----TYDGLVLSTHENVVVVVIQYRLG-------IW-----------GFFSTGDEH--SRGNWG 191

  Fly   205 LKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGNTLSPWA 269
            ..|||.||.||:.|.::||||..::||||:|||..||..::::.....||.:||..||
Mouse   192 HLDQVAALHWVQDNIAKFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFQRAISESG------- 249

  Fly   270 VTPQRNWPYRLAVQAGYAGENNTRDVWEFL------KNAKGSEIIKANGELCIDEEKKERIGFSF 328
                      :|:.||.. :.|||.:.|.:      ||...:.::.     |:.::.:|.:   .
Mouse   250 ----------VALTAGLV-KKNTRPLAEKIAVISGCKNTTSAAMVH-----CLRQKTEEEL---L 295

  Fly   329 GPVIE-------------------PYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNE-GLLLY 373
            |..::                   |.|....::||.|.|::.....|.:|.|:|....| |.:|
Mouse   296 GTTLKLNLFKLDLHGDSRQSHPFVPTVLDGVLLPKMPEEILAEKNFNTVPYIVGINKQEFGWIL- 359

  Fly   374 SETKTNPKCLNELDDCRFVVPIELNMDRESA--LCREYGDQLR----------QCYYGDKTPSLD 426
                  |..:|       ..|.::.:|:.:|  |.::....|.          :.|..||..:..
Mouse   360 ------PTMMN-------YPPSDVKLDQMTAMSLLKKSSFLLNLPEDAIAVAIEKYLRDKDYTGR 411

  Fly   427 TLHEYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTCHGD 491
            ...:.|:::....|..|  ..::||......||||:|.|.:.....:.::    ...|.|. |||
Mouse   412 NKDQLLELIGDVVFGVP--SVIVSRGHRDAGAPTYMYEFQYSPSFSSEMK----PDTVVGD-HGD 469

  Fly   492 DLSYLFYNSLARKLKNHTREYKCIERLVGLWTHFAACGNPNFD-----PE--QEDLWQPVDPAAV 549
            ::..:|...:.|. .....|....:.::..|.:||..||||..     ||  |::.:..:.....
Mouse   470 EIYSVFGAPILRG-GTSEEEINLSKMMMKFWANFARNGNPNGQGLPHWPEYDQKEGYLQIGATTQ 533

  Fly   550 EKHQLKCLNISDELKVIDVPDLKKLMVWESFFRRDEL 586
            :..:||               .|::..|.....:.:|
Mouse   534 QAQKLK---------------EKEVAFWTELLAKKQL 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	161/585 (28%)
		Aes	<115..>237	CDD:223730	50/125 (40%)
Ces1e	NP_598421.1	COesterase	25..546	CDD:278561	164/608 (27%)
		Aes	44..>242	CDD:223730	85/221 (38%)
		Prevents secretion from ER. /evidence=ECO:0000255	559..562

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832964
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740