Protein Alignment alpha-Est9 and Ces1c

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_031980.2
• Gene: Ces1c / 13884
• MGIID: 95420
• Length: 554
• Species: Mus musculus
• Alignment Length: 590
• Identity: 168/590 - (28%)
• Similarity: 259/590 - (43%)
• Gaps: 122/590 - (20%)

  Fly    33 VVSTTYGPIKGVKRKSIYG--QSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGP--- 92
            ||.||.|.:.| |..|:.|  |....|..:||||||:|.||:..|||.|.|:.|::.||..|
Mouse    25 VVDTTQGKVLG-KYISLEGFEQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNATSYPPMCS 88

  Fly    93 ------KPLQKHFVFEM----TDGSEDCLYLNVYT-KNLYPTKPMPVMVWIYGGGFQFGEASREC 146
                  |.|...|..|.    ...||||||||:|: .:|..:..:||||||:|||...|.||.
Mouse    89 QDAGWAKILSDMFSTEKEILPLKISEDCLYLNIYSPADLTKSSQLPVMVWIHGGGLVIGGASP-- 151

  Fly   147 YSPDYL-LREDVVVISINYRLGPLG---TNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKD 207
            |:...| ..|:|||::|.||||..|   |.|:                       ..|||....|
Mouse   152 YNGLALSAHENVVVVTIQYRLGIWGLFSTGDE-----------------------HSPGNWAHLD 193

  Fly   208 QVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGNTLSPWAVTP 272
            |:.|||||:.|.:.|||:..::||||:|:|..||..::::.....|||:||..||..::  ....
Mouse   194 QLAALRWVQDNIANFGGNPDSVTIFGESSGGISVSVLVLSPLGKDLFHRAISESGVVIN--TNVG 256

  Fly   273 QRNWPYRLAVQA--------GYAGENNTRDVWEFLKNAKGSEIIKANGELCIDEEKKERIGFSFG 329
            ::|      :||        ....:.::..:.:.|:....||:::.:|:|.       :...|..
Mouse   257 KKN------IQAVNEIIATLSQCNDTSSAAMVQCLRQKTESELLEISGKLV-------QYNISLS 308

  Fly   330 PVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNE-GLLLYSETKTNPKCLNELDDCRFVV 393
            .:|:     ..|:||.|.|::.....|.:|.|:|....| |.::       |..|..|      :
Mouse   309 TMID-----GVVLPKAPEEILAEKSFNTVPYIVGFNKQEFGWII-------PMMLQNL------L 355

  Fly   394 PI-ELNMDRESALCREYGDQL-----------RQCYYGDKTPSLDTLHEYLQMVSHEYFWFPIYR 446
            |. ::|.:..|.|.|.:..:|           .|...|...|:..: ...|.|....:|..|  .
Mouse   356 PEGKMNEETASLLLRRFHSELNISESMIPAVIEQYLRGVDDPAKKS-ELILDMFGDIFFGIP--A 417

  Fly   447 TVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTCHGDDLSYLFYNSLARKLKNHTRE 511
            .:|||........||:|.|.:.....:..|    .:.|.|. |||::.::|...|.::..:. .|
Mouse   418 VLLSRSLRDAGVSTYMYEFRYRPSFVSDKR----PQTVEGD-HGDEIFFVFGAPLLKEGASE-EE 476

  Fly   512 YKCIERLVGLWTHFAACGNPN---------FDPEQEDLWQPVDPAAVEKHQLKCLNIS--DELKV 565
            ....:.::..|.:||..||||         :| |||...| :.....:..:||...::  .||..
Mouse   477 TNLSKMVMKFWANFARNGNPNGEGLPHWPEYD-EQEGYLQ-IGATTQQAQRLKAEEVAFWTELLA 539

  Fly   566 IDVPD 570
            .:.|:
Mouse   540 KNPPE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	168/590 (28%)
Ces1c	NP_031980.2	Esterase_lipase	25..525	CDD:238191	163/569 (29%)
		Prevents secretion from ER. /evidence=ECO:0000255	551..554