Protein Alignment alpha-Est9 and Nlgn2

DIOPT Version :9

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_446444.1
• Gene: Nlgn2 / 117096
• RGDID: 621118
• Length: 836
• Species: Rattus norvegicus
• Alignment Length: 630
• Identity: 166/630 - (26%)
• Similarity: 258/630 - (40%)
• Gaps: 171/630 - (27%)

  Fly    33 VVSTTYGPIKGVKRK---SIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGPK- 93
            ||:|.||.::||:|:   .|.| ....|..:|:|.||:|..|::.|:.|..|..||:.|:..|.
  Rat    43 VVNTAYGRVRGVRRELNNEILG-PVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPAC 106

  Fly    94 PLQKHFVFE-------MTDG-----------SEDCLYLNVYTKNLYPTK--PM------------ 126
            |...|....       .||.           ||||||||:|.    ||:  |:
  Rat   107 PQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYV----PTEDGPLTKKRDEATLNPP 167

  Fly   127 ----------PVMVWIYGGGFQFGEASRECYSPDYLLR-EDVVVISINYRLGPLGTNDDTWKKKH 180
                      |||::::||.:.  |.:...:....|.. .:|:|.::|||||.|
  Rat   168 DTDIRDSGKKPVMLFLHGGSYM--EGTGNMFDGSVLAAYGNVIVATLNYRLGVL----------- 219

  Fly   181 IFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMM 245
                   |||...|..  ..||.||.||:.||||:..|.:.||||...|||||..||::.|:.::
  Rat   220 -------GFLSTGDQA--AKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLI 275

  Fly   246 ITEQTHGLFHKAICMSGNTLSPWAVTPQRNWPYR----LAVQAGYAGENNTRDVWEFLKNAKGSE 306
            ::..:.|||.|||..||..:|.|:|..|   |.:    ||.:.|...|::|..| |.|:.
  Rat   276 LSHHSEGLFQKAIAQSGTAISSWSVNYQ---PLKYTRLLAAKVGCDREDSTEAV-ECLRR----- 331

  Fly   307 IIKANGELCIDEEKKERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGLL 371
              |::.||...:.:..|...:||||::     ..|||..|..:|:.....|..::||....|||.
  Rat   332 --KSSRELVDQDVQPARYHIAFGPVVD-----GDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLK 389

  Fly   372 LYSETKTNPK---------CLNELDDCRFVVPIELNMDRESA-------LCREYGDQLRQCYYGD 420
            ...::..:..         .::...|..:..|...::.||:.       ..|:.|:..|:...
  Rat   390 FVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLL-- 452

  Fly   421 KTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVR 485
               :|.|.|:::.         |...|......|  .:|.|.|.|      ::|     |..:.|
  Rat   453 ---ALFTDHQWVA---------PAVATAKLHADY--QSPVYFYTF------YHH-----CQAEGR 492

  Fly   486 ----GTCHGDDLSYLFYNSLARKLK----NHTREYKCIERLV-GLWTHFAACGNPNFDPEQEDLW 541
                ...|||:|.|:|...:.....    |.::....:..:| ..||:||..|:||
  Rat   493 PEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN--------- 548

  Fly   542 QPVDPAAVEKHQLKCLNISDELKVIDV-PDLKKLMVWESFFRRDE 585
            |||               ..:.|.|.. |:..:.:||..|..:::
  Rat   549 QPV---------------PQDTKFIHTKPNRFEEVVWSKFNSKEK 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	33..555	CDD:278561	160/597 (27%)
		Aes	<115..>237	CDD:223730	43/146 (29%)
Nlgn2	NP_446444.1	COesterase	42..601	CDD:395084	166/630 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	623..661
		Required for interaction with LHFPL4. /evidence=ECO:0000250|UniProtKB:Q69ZK9	679..699
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	711..735
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	791..836

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336480
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840