Protein Alignment alpha-Est9 and CES1

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: NP_001020366.1
• Gene: CES1 / 1066
• HGNCID: 1863
• Length: 568
• Species: Homo sapiens
• Alignment Length: 537
• Identity: 158/537 - (29%)
• Similarity: 240/537 - (44%)
• Gaps: 80/537 - (14%)

  Fly    29 SEKTVVSTTYGPIKGVKRKSIYG--QSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQG 91
            |...||.|.:|.:.| |..|:.|  |....|..|||||||:|.||:..|||.|.|:.|::.||..
Human    22 SSPPVVDTVHGKVLG-KFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYP 85

  Fly    92 P----KPLQKHFVFEMTDG---------SEDCLYLNVYT-KNLYPTKPMPVMVWIYGGGFQFGEA 142
            |    .|.....:.|:...         ||||||||:|| .:|.....:||||||:|||...|.|
Human    86 PMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAA 150

  Fly   143 SRECYSPDYL---LREDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAG 204
            |    :.|.|   ..|:|||::|.||||       .|           ||....|..  ..||.|
Human   151 S----TYDGLALAAHENVVVVTIQYRLG-------IW-----------GFFSTGDEH--SRGNWG 191

  Fly   205 LKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGNTLSPWA 269
            ..|||.|||||:.|.:.|||:..::||||:|||..||..::::.....|||:||..||..|:...
Human   192 HLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 256

  Fly   270 VTPQRNWPY--RLAVQAGYAGENNTRDVW-EFLKNAKGSEIIKANGE---LCID-----EEKKER 323
            |......|.  ::|:.||.  :..|..|. ..|:.....|:::...:   |.:|     .|.:..
Human   257 VKKGDVKPLAEQIAITAGC--KTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPL 319

  Fly   324 IGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNE-GLLLYSETKTNPKCLNELD 387
            :|         .|....::.|.|.|:......:.:|.::|....| |.|:..:..:.|....:||
Human   320 LG---------TVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLD 375

  Fly   388 DCRFVVPIELNMDRESALC--REYGDQLRQCYYGDKTPSLDTLHEYLQMVSHEYFWFPIYRTVLS 450
            .   ...:.|.......:|  :|...:..:.|.|....::.....:|.:::...|..|  ..:::
Human   376 Q---KTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVP--SVIVA 435

  Fly   451 RLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTCHGDDLSYLFYNSLARKLKNHTREYKCI 515
            |......||||:|.|.:.....:.::    .|.|.|. |||:|..:|.....::..:. .|.:..
Human   436 RNHRDAGAPTYMYEFQYRPSFSSDMK----PKTVIGD-HGDELFSVFGAPFLKEGASE-EEIRLS 494

  Fly   516 ERLVGLWTHFAACGNPN 532
            :.::..|.:||..||||
Human   495 KMVMKFWANFARNGNPN 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	157/534 (29%)
CES1	NP_001020366.1	COesterase	23..548	CDD:395084	157/536 (29%)