DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment alpha-Est9 and Ces1f

DIOPT Version :10

Sequence 1:NP_731165.2 Gene:alpha-Est9 / 40897 FlyBaseID:FBgn0015577 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001096829.2 Gene:Ces1f / 100125372 RGDID:1642419 Length:561 Species:Rattus norvegicus


Alignment Length:599 Identity:179/599 - (29%)
Similarity:251/599 - (41%) Gaps:143/599 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 SEKTVVSTTYGPIKGVKRKSIYG--QSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQG 91
            |...||.||.|.:.| |..|:.|  ||...|..:||||||:|.||:..|||.|.|:.|::.|:..
  Rat    21 SSPPVVDTTKGKVLG-KYVSLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYP 84

  Fly    92 PKPLQK------------------HFVFEMTDGSEDCLYLNVY-----TKNLYPTKPMPVMVWIY 133
            |...|.                  |..|     ||||||||:|     |||    ..:||||||:
  Rat    85 PMCSQDAAKGQRMNDLLTNRKEKIHLEF-----SEDCLYLNIYTPADFTKN----SRLPVMVWIH 140

  Fly   134 GGGFQFGEASRECYSPDYL-LREDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPEL 197
            |||...|.||  .|....| ..|:|||::|.||||       .|           ||....|.. 
  Rat   141 GGGMTLGGAS--TYDGRVLSAYENVVVVAIQYRLG-------IW-----------GFFSTGDEH- 184

  Fly   198 DVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSG 262
             ..||.|..|||.||.||:.|.:.||||..::||||:|||..||..::::..|..|||:||..||
  Rat   185 -SRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVSVLVLSPLTKNLFHRAISESG 248

  Fly   263 NTLSPWAVTPQ-RNWPYRLAVQAGYAGENNTRDV----------WEFLKNAKGSEIIKANGELCI 316
            ....|..:|.. |....::|..||.  |..|..:          .|.|:..|...:||.:.:   
  Rat   249 VVFLPGLLTKDVRPAAKQIADMAGC--ETTTSAIIVHCLRQKTEEELLEIMKKMNLIKLSSQ--- 308

  Fly   317 DEEKKERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNE-GLLLYSETKTNP 380
             .:.||...|.      ..|..:.|:||.|.|::.....|.:|.|:|....| |.||       |
  Rat   309 -RDNKESYHFL------STVVDNVVLPKDPKEILAEKNFNTVPYIVGINKQECGWLL-------P 359

  Fly   381 KCLNELDDCRFVVPIELNMDRESA--LCREYGDQLRQCYYG------------------DKTPSL 425
            ..:.       .||.::.:|::.|  |..::..     .||                  |.....
  Rat   360 TMMG-------FVPADVELDKKMAITLLEKFAS-----LYGIPEDIIPVAIEKYRKGSDDSIKIR 412

  Fly   426 DTLHEYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTCHG 490
            |.:..::..||     |.|...::||......||||:|.:.:.....:..|    .|.|.|. |.
  Rat   413 DGILAFIGDVS-----FSIPSVMVSRDHRDAGAPTYMYEYQYYPSFSSPQR----PKHVVGD-HA 467

  Fly   491 DDLSYLFYNSLARKLKNHTREYKCIERLVGLWTHFAACGNPN---------FDPEQEDLWQPVDP 546
            |||..:|...:.|...:. .|.|..:.::..|.:||..||||         :|.::|.|  .:..
  Rat   468 DDLYSVFGAPILRDGASE-EEIKLSKMVMKFWANFARNGNPNGRGLPHWPQYDQKEEYL--QIGA 529

  Fly   547 AAVEKHQLKCLNIS 560
            ...:..:||...::
  Rat   530 TTQQSQRLKAEEVA 543

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est9NP_731165.2 COesterase 32..577 CDD:395084 178/596 (30%)
Ces1fNP_001096829.2 COesterase 22..545 CDD:395084 178/598 (30%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 558..561
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.