Protein Alignment alpha-Est9 and nlgn1

DIOPT Version :10

• Sequence 1: NP_731165.2
• Gene: alpha-Est9 / 40897
• FlyBaseID: FBgn0015577
• Length: 587
• Species: Drosophila melanogaster
• Sequence 2: XP_017213657.1
• Gene: nlgn1 / 100002610
• ZFINID: ZDB-GENE-090918-1
• Length: 867
• Species: Danio rerio
• Alignment Length: 686
• Identity: 173/686 - (25%)
• Similarity: 263/686 - (38%)
• Gaps: 234/686 - (34%)

  Fly    29 SEK-----TVVSTTYGPIKGVKRK---SIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVR 85
            |||     .:|:||||.::|.|::   .|.| ....|..:|:|.||.||.|::.|:||..|:|:|
Zfish    46 SEKLDETDPIVTTTYGKVRGFKKELNNEILG-PVIQFLGVPYAAPPTGERRFQPPEPPISWSEIR 109

  Fly    86 SCTSQGPKPLQKHFVFE----------------------MTDGSEDCLYLNVYTKNLYPTK---- 124
            :.|...|...|.  :.|                      :.|.|||||:||:|.    ||:
Zfish   110 NATQFAPVCPQT--LLEGRLPDVMLPVWFTNSIEVVSSYVQDQSEDCLFLNIYV----PTEDVKR 168

  Fly   125 --------------------------------------------PMPVMVWIYGGGFQFGEASRE 145
                                                        |.||||:::||.:.  |.:..
Zfish   169 ISKECARKPGKKICRKGGPLSKKQNDDLADNDGAEDEDIRESGSPKPVMVFVHGGSYM--EGTGN 231

  Fly   146 CYSPDYLLR-EDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQV 209
            .:....|.. .:|:||::|||||.|                  |||...|..  ..||.||.|.:
Zfish   232 MFDGSILASYGNVIVITVNYRLGVL------------------GFLSTGDQA--AKGNYGLLDLI 276

  Fly   210 LALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMI---------TEQTHGLFHKAICMSGNTL 265
            .||||...|.:.||||...||:||..||::.|:.:.:         :..|.|||.:||..||..|
Zfish   277 QALRWTSENIAFFGGDPLRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 341

  Fly   266 SPWAVTPQ-RNWPYRLAVQAGYAGENNTRDVWEFLKNAKGSEIIKANGELCIDEEKKERIGFSFG 329
            |.|||:.| ..:...||.:.|.    |.:|..|.::..:.    |...||...:.:..|...:||
Zfish   342 SSWAVSFQPAKYARMLAKKVGC----NLKDTVEMVECLQK----KHYKELVEQDIQPARYHIAFG 398

  Fly   330 PVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGLLLYSETKTNPKCLNELDDCRFVVP 394
            |||:     ..|:|..|..:|......|..:::|....|||                   :||
Zfish   399 PVID-----GDVIPDDPQILMEQGEFLNYDIMLGVNQGEGL-------------------KFV-- 437

  Fly   395 IELNMDRESALCRE-------------YG-----DQLRQC---YYGD----KTPSLDTLHEYLQM 434
             ||.:|.|:.:...             ||     |.||:.   .|.|    ..|  :|..:.|..
Zfish   438 -ELIVDNENGVQANDFDYAVSSFVDDLYGYPEGKDILRETIKFMYTDWADRHNP--ETRRKTLLA 499

  Fly   435 VSHEYFWF-PIYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKV---RGTCHGDDLSY 495
            :..::.|. |...|  :.|..:..:|||.|.|      ::|.:.    ::|   ....|||::.|
Zfish   500 LFTDHQWVAPAVAT--ADLHSSFGSPTYFYAF------YHHCQT----EQVPPWADAAHGDEIPY 552

  Fly   496 LFYNSLARKLKNHTREYKC--------IERLV-GLWTHFAACGNPNFDPEQEDLWQPVDPAAVEK 551
            :|    ...:...|..:.|        :..:| ..||:||..|:||         |||
Zfish   553 VF----GLPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN---------QPV------- 597

  Fly   552 HQLKCLNISDELKVIDV-PDLKKLMVWESFFRRDEL 586
                    ..:.|.|.. |:..:.:.|..:.::|:|
Zfish   598 --------PQDTKFIHTKPNRFEEVAWTRYNQKDQL 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est9	NP_731165.2	COesterase	32..577	CDD:395084	167/667 (25%)
nlgn1	XP_017213657.1	COesterase	53..647	CDD:395084	170/679 (25%)