Protein Alignment alpha-Est10 and Ces1h

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 535
• Identity: 156/535 - (29%)
• Similarity: 225/535 - (42%)
• Gaps: 112/535 - (20%)

  Fly    64 NTIWG---GSYFSFE----------KIPFAKPPVGDLRFKAPEAVEPWDQELDCTSPADKPLQTH 115
            ||..|   |.|.|.|          .:||||||:|.|||..|:..|||....:.||......|..
Mouse    27 NTTHGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATSYPPMCSQDA 91

  Fly   116 MFFR-------------KYAGSEDCLYLNVYVK-DLQPDKLR-PVMVWIYGGGYQVGEAS----R 161
            :..:             :...||||||||||.. ||..:..| ||||||:|||..||.||    |
Mouse    92 VLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLVVGGASAYDGR 156

  Fly   162 DMYSPDFFMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSN 226
            .:.:     .::||:||:.|||...||.|..|....  ||.|..||:.||.|:|.||..||||..
Mouse   157 TLSA-----HENVVVVTIQYRLAIWGFFSTGDEHSR--GNWGHLDQLAALHWIQDNIANFGGDPG 214

  Fly   227 NITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNNWAYRLAQKLGYTGDNK- 290
            ::|:||:||||.|...|.|||..:.|.|:||..||.|   :|.......|..:.:::..|...|
Mouse   215 SVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVV---FTSGLFMEDASSVTEQIAVTAGCKT 276

  Fly   291 -----------DKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQ 344
                       .|...|.|..|....:.|..|.  .|.:|::..|        |...:..|:.|.
Mouse   277 TTSAVIVHCLRQKTEEELLEIMQKMNLFKLDAQ--ENTKKNYPFL--------PTVLDGVVLPKA 331

  Fly   345 PHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYG 409
            |..::.....:.:|.:.|....|.....|.:...|             |:|  :.||.|:   ..
Mouse   332 PEAILAEKNFNTVPYIVGINKQEFGWTLPMIMEFP-------------PTD--VKLDKKV---IS 378

  Fly   410 LQLKK-AYF------------------GDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSS 455
            |.|:| |||                  .|:|..  |.:..|:|.....|..|....:... |.:.
Mouse   379 LFLRKLAYFFNIPEDGIPVAIEKYSKGTDDPIQ--NRVWLLQLIGDVMFGIPSVIVSRGH-RDAG 440

  Fly   456 APTYLYRFDHDSKLCNAIR-IVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDV 519
            ||||:|.|.......:.:: ..:.|.      |||::..:|.:.:..:.:.:. |..:...|:..
Mouse   441 APTYMYEFQSRPSFSSELKPKTVTGD------HGDEVYSVFGAPILREGSSEE-EINLSKMMMKF 498

  Fly   520 WTSFAAHGDPNCESI 534
            |.:||.:|:||.:.:
Mouse   499 WANFARNGNPNGQGL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	156/535 (29%)
		Aes	<132..>279	CDD:223730	66/152 (43%)
Ces1h	NP_001357759.1	COesterase	24..546	CDD:365897	156/535 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832593
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740