Protein Alignment alpha-Est10 and nlgn3a

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 649
• Identity: 169/649 - (26%)
• Similarity: 245/649 - (37%)
• Gaps: 202/649 - (31%)

  Fly    48 YSVIKTKSGPVRGVK---RNTIWG--GSYFSFEKIPFAKPPVGDLRFKAPEAVEPW--------- 98
            |..:.|:.|.:||.:   .:.|.|  ..|..   :|:|.||||:.||..||....|
Zfish    68 YPTVNTQYGKLRGARVPLHSEILGPVDQYLG---VPYATPPVGEKRFLPPEPPSSWSGIKNATHF 129

  Fly    99 -----------------------DQELDCTSPADKPLQTHMFFRKYAGSEDCLYLNVYV------ 134
                                   :.::..||..|:             :|||||||:||
Zfish   130 APVCPQNIHNAVPEIMMPIWFTFNLDIVATSIQDQ-------------NEDCLYLNIYVPTEDVK 181

  Fly   135 -------------------------------------KDLQPDKLRPVMVWIYGGGYQVGEASRD 162
                                                 :|::....:||||:|:||.|.  |.:.:
Zfish   182 RISKECTRKPNKKICRKGGTHSKKQGEDLSDNDGDEDEDIRDTGAKPVMVYIHGGSYM--EGTGN 244

  Fly   163 MYSPDFFMS-KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSN 226
            |.......| .:|:::|:.:|:|.|||||..|..  ..||.||.|||.||||:.:||..||||||
Zfish   245 MIDGSVLASYGNVIVITLNFRVGVLGFLSTGDQA--AKGNYGLLDQIQALRWISENIGYFGGDSN 307

  Fly   227 NITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWT---QPPRNNWAYRLAQKLGYTG- 287
            .||:||...|.:....|.||..:|||.|:||:.|||.|..|.   ||.:  :...||:|:|...
Zfish   308 RITVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSALSSWAVNYQPVK--YTRLLAEKVGCNVL 370

  Fly   288 DNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNS 352
            |..|  :.:.||..|..|:|:       .|.:..|...|||||:     :..|:...|..||:..
Zfish   371 DTLD--MVDCLRKKSARELVE-------QDIQPARYHVAFGPVI-----DGDVIPDDPEILMEQG 421

  Fly   353 WSHRIPMMFGGTSFEGLLFYPEVSRRPATLDE----VGNCKNLLPSDL--GLNLDPKLRENYGLQ 411
            ......:|.|....|||.|...|      :|.    .||..:...||.  .|...|:.::.....
Zfish   422 EFLNYDIMLGVNQGEGLRFVENV------VDSEDGVSGNDFDFSVSDFVDSLYGYPEGKDTLRET 480

  Fly   412 LKKAY--FGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIR 474
            :|..|  :.|....:......:.|.:..::..|....|....|..| |||.|.|.|.
Zfish   481 IKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGS-PTYFYAFYHH-------- 536

  Fly   475 IVLCGHQMR----GVCHGDDLCYIF------------------HSMLSHQSAPDSPEHKVITGMV 517
               |...|:    ...|||::.|:|                  ..|||             ..::
Zfish   537 ---CQSLMKPAWSDAAHGDEVPYVFGIPMIGPTDLFPCNFSKNDIMLS-------------AVVM 585

  Fly   518 DVWTSFAAHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPELQKIEPVWNSFYAPNKL 581
            ..||:||..||||         .|:...|.| .....::||          |..|:.:...::|
Zfish   586 TYWTNFAKTGDPN---------KPVPQDTKF-IHTKANRFE----------EVAWSKYNPQDQL 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	160/598 (27%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:395084	168/648 (26%)