Protein Alignment alpha-Est10 and nlgn2a

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_009301340.1
• Gene: nlgn2a / 556158
• ZFINID: ZDB-GENE-090918-2
• Length: 828
• Species: Danio rerio
• Alignment Length: 609
• Identity: 181/609 - (29%)
• Similarity: 258/609 - (42%)
• Gaps: 145/609 - (23%)

  Fly    48 YSVIKTKSGPVRGVKR---NTIWG--GSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSP 107
            |..:.|..|.:||:|:   |.|.|  ..|..   :|:|..|:||.||:.|||...|.:..:.|..
Zfish    46 YPTVTTNYGKLRGIKKELNNEILGPVEQYLG---VPYATAPIGDRRFQPPEAPGSWQEVRNATQF 107

  Fly   108 ADK-PLQTH---------MFFRKYAG---------SEDCLYLNVYV------------------- 134
            |.. |...|         ::|.....         |||||||||||
Zfish   108 APVCPQNVHGVLPEIMLPVWFTDSLDVAATYIQNQSEDCLYLNVYVPTEDGPLTKKHDESTLNRP 172

  Fly   135 --KDLQPDKLRPVMVWIYGGGYQVGEASRDMYSPDFFMS-KDVVIVTVAYRLGALGFLSLDDPQL 196
              :|::..:.:|||::|:||.|.  |.:.:|:......: .:|::||:.||||.|||||..|.
Zfish   173 RDEDIRDRRKKPVMLFIHGGSYM--EGTGNMFDASVLAAYGNVIVVTMNYRLGVLGFLSTGDQ-- 233

  Fly   197 NVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSG 261
            :..||.||.|||.||||:.:||..||||...||:||..||.:..:.|.||..:|||..:||..||
Zfish   234 SAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQRAIAQSG 298

  Fly   262 SVLCPWT---QPPRNNWAYRLAQKLGYT-GDNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHR 322
            |.:..|:   ||.:  :...||:|:|.| |:..|  :.:.||..:..|:|       ..|.:..|
Zfish   299 SAISSWSISYQPLK--YTKILARKVGCTYGETAD--LVDCLRRKNFRELV-------DQDIQPAR 352

  Fly   323 ILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEVG- 386
            ...|||||:     :..||...|..|||........::.|....|||.|..:    ..|..|.|
Zfish   353 YHIAFGPVM-----DGDVVPDDPEILMQQGEFLNYDLLIGVNQGEGLKFVDD----GGTESEEGI 408

  Fly   387 -------NCKNLLPSDLGLNLDPK----LRENYGLQLKKAY--FGDEPCNQANMMKFLELCSYRE 438
                   ...|.:.:..|.   ||    |||.    :|..|  :.|....:......|.|.:..:
Zfish   409 SAAAFDYTISNFVDNLYGY---PKGKDILRET----IKFMYTDWADRDNGEMRRKTLLALFTDHQ 466

  Fly   439 FWHP-IYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMR----GVCHGDDLCYIFHSM 498
            :..| |..|.|:...||  |.|.|.|.|.           |..:.|    ...|||::.|:|...
Zfish   467 WVAPAIATAKLHADYQS--PVYFYTFYHH-----------CQTETRPEWADAAHGDEIPYVFGVP 518

  Fly   499 LSHQSAPD------SPEHKVITGMV-DVWTSFAAHGDPNCESIKSLKFAPIENVTNFKCLNIGDQ 556
            :.  .|.|      |....:::.:| ..||:||..||||....:..||  |....|        :
Zfish   519 MI--GATDLFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNLPVPQDTKF--IHTKPN--------R 571

  Fly   557 FEVMALPELQKIEPVWNSFYAPNK 580
            ||          |.:|..|.:.:|
Zfish   572 FE----------EVIWTKFNSKDK 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	170/559 (30%)
nlgn2a	XP_009301340.1	COesterase	47..608	CDD:395084	180/608 (30%)