Protein Alignment alpha-Est10 and Nlg3

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001036685.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 699
• Identity: 169/699 - (24%)
• Similarity: 255/699 - (36%)
• Gaps: 236/699 - (33%)

  Fly    50 VIKTKSGPVRGVKRNTIWGGSYF----SFEKIPFAKPPVGDLRFKAPEAVEPWD--QELDCTSPA 108
            :|.|::|.:.||....  .|.:.    ::..||:|.||||:|||..|.:...|.  ::.|..||.
  Fly   157 IINTRNGAISGVIVQL--DGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPV 219

  Fly   109 ------DKPLQTHMFFRKYAG---------------SEDCLYLNVYV------KDL--------- 137
                  |...:|....|...|               ||||||||:||      :|.
  Fly   220 CPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSA 284

  Fly   138 ---------------------------QPDKLRPVMVWIYGGGYQVGEASRDMYSPDFFMS-KDV 174
                                       .|.|. ||:|:::|..|:..  |.:.|......| ..:
  Fly   285 GSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKY-PVLVFVHGESYEWN--SGNPYDGSVLASYGQI 346

  Fly   175 VIVTVAYRLGALGFLSLD-DPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGA 238
            ::||:.||||.||||:.: |....:|.|.||.|.|.||.|:::||.|||||.|:|||.|...|.|
  Fly   347 LVVTINYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAA 411

  Fly   239 STHFLALSPQT-EGLI-HKAIVMSGSVLCPW---TQPPRNNWAYRLAQKLGYTGDNKDKAIFEFL 298
            ..|||..|... |||: ::||:||||.|.||   :.|.:  :|..:|..:....|.....:.:.|
  Fly   412 CVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAK--YAAIVAHHVNCASDLPHAHLMKCL 474

  Fly   299 RSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPMMFGG 363
            |.       |....:||...:.....|||||.::                              |
  Fly   475 RE-------KTLDQLLSVPIRPPEFGFAFGPSID------------------------------G 502

  Fly   364 TSFEGLLFYPEVSRRPATLDE------VGNCKNLLPSDLGLNL-----DPKLRENYGLQLKKA-- 415
            ...:|..:.|.....||...:      .||.   |..:.|:..     .|...||..|..|.|
  Fly   503 VVIDGGDYVPPAPGSPAAQAQAQASTAAGNG---LGGEAGIAAAGGWGTPGQLENIVLMRKTAIN 564

  Fly   416 -------------------------YFGDEPCNQANMMK--------------FLELCSYREFW- 440
                                     .:|.|...::.::|              |..:.:....|
  Fly   565 KLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWE 629

  Fly   441 ----HPI---------------YRAALNRVRQSSAP---TYLYRFDHDSKLCNAIRIVLCGHQMR 483
                |||               ...|...|...||.   :|||.||:.::..:.       .|.:
  Fly   630 RPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHRNSYLYVFDYQTRFGDY-------PQRQ 687

  Fly   484 GVCHGDDLCYIFHSML----SHQSAP-DSPEHKVITGMVDVWTSFAAHGDPNCE----------- 532
            |..||:||.|||.:.|    :|.:.. ...|..:...::..|::|...|:||.:
  Fly   688 GCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGSRQER 752

  Fly   533 -SIKSLKFAPIENVTNFKCLNIGDQ-------------FEVMALPELQK 567
             ..|::::...|:| :.|.||...:             |.:..:|:|.|
  Fly   753 SRYKTIEWTAYESV-HKKYLNFDTKPKLKNHYRAHRLSFWLNLIPDLHK 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	160/659 (24%)
		Aes	<132..>279	CDD:223730	65/195 (33%)
Nlg3	NP_001036685.2	COesterase	151..791	CDD:278561	165/688 (24%)
		Aes	<313..>410	CDD:223730	42/99 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440338
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740