DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Est10 and Est-6

DIOPT Version :9

Sequence 1:NP_001246962.1 Gene:alpha-Est10 / 40896 FlyBaseID:FBgn0015569 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_001261749.1 Gene:Est-6 / 39392 FlyBaseID:FBgn0000592 Length:544 Species:Drosophila melanogaster


Alignment Length:546 Identity:154/546 - (28%)
Similarity:257/546 - (47%) Gaps:77/546 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 VIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAV-EPWDQELDCTSPADKPLQ 113
            :::...|.:||  |:   .|||:|:|.||:|:||.|||||:|||.. :.|....|.|......||
  Fly    29 LVQLPQGKLRG--RD---NGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQ 88

  Fly   114 THMF---FRKYAGSEDCLYLNVYVKDLQPDKLRPVMVWIYGGGYQVGEASRDMYSPDFFMSKDVV 175
            ...|   ..|..|.||||.::||..........||:..|:||.:..|.|.::.:. :.......:
  Fly    89 WDQFTPGANKLVGEEDCLTVSVYKPKNSKRNSFPVVAHIHGGAFMFGAAWQNGHE-NVMREGKFI 152

  Fly   176 IVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGAST 240
            :|.::||||.|||:|..|..|  |||.|||||.:||:|::|||.:|||:..|:.|.|.||||||.
  Fly   153 LVKISYRLGPLGFVSTGDRDL--PGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASV 215

  Fly   241 HFLALSPQTEGLIHKAIVMSGSVLCPWT-QPPRNNWAYRLAQKLGYTGDNKDKAIFEFLRSMSGG 304
            |...|......|...|...||:.|.||. |......|:.|.:.:|........::.:.|:|....
  Fly   216 HLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELGRNVGCESAEDSTSLKKCLKSKPAS 280

  Fly   305 EIVKATATVLSNDEKHHRILFA-FGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPMMF------G 362
            |:|.|....|.    ...:.|| |.||:||......::.:.|.:::::....::|...      |
  Fly   281 ELVTAVRKFLI----FSYVPFAPFSPVLEPSDAPDAIITQDPRDVIKSGKFGQVPWAVSYVTEDG 341

  Fly   363 GTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKL-----------RENYGLQLKKAY 416
            |  :...|...| .:....:|::        ::..|.|.|.|           .::|..::|:.|
  Fly   342 G--YNAALLLKE-RKSGIVIDDL--------NERWLELAPYLLFYRDTKTKKDMDDYSRKIKQEY 395

  Fly   417 FGDEPCNQANMMKFLELCSYREFWHPIYRAA------LNRVRQSSAPTYLYRFDHDSKLCNAIRI 475
            .|::   :.::..:.||  .|.|...:::.:      |:| :...:|.|.|.:|:.::  ..|..
  Fly   396 IGNQ---RFDIESYSEL--QRLFTDILFKNSTQESLDLHR-KYGKSPAYAYVYDNPAE--KGIAQ 452

  Fly   476 VLCGHQMR--GVCHGDDLCYIFHSMLSHQSAPDSPEHKVIT-GMVDVWTSFAAHGDPNCESIKSL 537
            ||......  |..||||...||.:.:  :.....|:.::|: ..:::...||:..:      .||
  Fly   453 VLANRTDYDFGTVHGDDYFLIFENFV--RDVEMRPDEQIISRNFINMLADFASSDN------GSL 509

  Fly   538 KFAPIENVTNFKCLNIG-DQFEVMAL 562
            |:...:    ||. |:| ::|:::|:
  Fly   510 KYGECD----FKD-NVGSEKFQLLAI 530

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Est10NP_001246962.1 COesterase 49..542 CDD:278561 148/523 (28%)
Aes <132..>279 CDD:223730 57/147 (39%)
Est-6NP_001261749.1 Esterase_lipase 29..537 CDD:238191 154/546 (28%)
Aes <110..>243 CDD:223730 54/135 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45440363
Domainoid 1 1.000 98 1.000 Domainoid score I1867
eggNOG 1 0.900 - - E2759_KOG1516
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D222591at33208
OrthoFinder 1 1.000 - - FOG0000017
OrthoInspector 1 1.000 - - otm46967
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X33
87.750

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