Protein Alignment alpha-Est10 and Ces1b

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001074841.1
• Gene: Ces1b / 382044
• MGIID: 3779470
• Length: 567
• Species: Mus musculus
• Alignment Length: 548
• Identity: 160/548 - (29%)
• Similarity: 231/548 - (42%)
• Gaps: 128/548 - (23%)

  Fly    66 IWG----------------GSYFSFE----------KIPFAKPPVGDLRFKAPEAVEPWDQELDC 104
            |||                |.|.|.|          .:||||||:|.|||..||..|||....:.
Mouse    16 IWGHSPSSPVVDTTQGKILGKYTSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNA 80

  Fly   105 TS--------PADKPLQTHMFFRKYAG-----SEDCLYLNVY-VKDLQPDKLRPVMVWIYGGGYQ 155
            ||        .....|.:.|...|...     ||||||||:| ..||....|.||||||:|||..
Mouse    81 TSYPPMCSQDAVAVQLLSDMLSTKKESIPPLFSEDCLYLNIYSPADLTKSSLLPVMVWIHGGGLM 145

  Fly   156 VGEASRDMYSPDFFMS--KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNI 218
            .|.||  :|: ...:|  ::||:||:.||||..|..|..|....  ||....||:.||||||.||
Mouse   146 TGGAS--LYN-GLALSAHENVVVVTIQYRLGIWGLFSTGDEHSR--GNWAHLDQLAALRWVQDNI 205

  Fly   219 EAFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVL-----------CPWTQPPR 272
            ..|||:.:::|:||.||||.|...|.|||..:.|.|:||..|..||           |..:|
Mouse   206 ANFGGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLENIVITLDLVACDLSQ--- 267

  Fly   273 NNWAYRLAQKLGYTGDNKDKAIFEFLRSMSGGEI----VKATATVLSNDEKHHRILFAFGPVVEP 333
                  :...:....|....|:.:.||..:..|:    ||...|.:.......:...:...|:
Mouse   268 ------MIATVSGCNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAASAKKDNTSMSTVI-- 324

  Fly   334 YTTEHTVVAKQPHELM---------------QNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLD 383
               :..|:.|.|.|::               :..:...||.|.|....||     :::...|:|
Mouse   325 ---DGVVLPKAPEEILAEKSFSTVPYIVGFNKQEFGWIIPTMLGDLLSEG-----KMNEETASL- 380

  Fly   384 EVGNCKNLL---PSDLGL--NLDPKLRENYGLQLKKAYFGDEPCNQANMMKFLELCSYREFWHPI 443
                   ||   .|||.:  :|.|.:.|.|   |:..   |:|..:.:::    |..:.:.:..|
Mouse   381 -------LLRRFHSDLNISESLIPAVIEKY---LRGT---DDPAKKRDLL----LDMFSDVFFGI 428

  Fly   444 YRAALNR-VRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDS 507
            ....|:| :|.:...||:|.|.:.....:..|    ...:.| .|||::..:|...|..:..  |
Mouse   429 PAVLLSRSLRDAGVSTYMYEFRYRPSFVSDKR----PQTVEG-DHGDEIFSVFGIPLLKEGT--S 486

  Fly   508 PEHKVITGMV-DVWTSFAAHGDPNCESI 534
            .|...::.|| ..|.:||.:|:||.|.:
Mouse   487 EEETNLSKMVMKFWANFARNGNPNGEGL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	160/548 (29%)
		Aes	<132..>279	CDD:223730	65/160 (41%)
Ces1b	NP_001074841.1	COesterase	19..547	CDD:278561	157/545 (29%)
		Aes	<121..>239	CDD:223730	56/122 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832610
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740