Protein Alignment alpha-Est10 and Gli

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Alignment Length: 598
• Identity: 163/598 - (27%)
• Similarity: 237/598 - (39%)
• Gaps: 168/598 - (28%)

  Fly    74 FEKIPFAKPPVGDLRFKAPEAVEPWD--QELDCTSPADKPLQTHMFFRKYAGS--------EDCL 128
            |..||:|.||..:.|||.|.....|.  |.:|......:|:       :|.|:        ||||
  Fly   178 FLGIPYALPPTFEGRFKPPRVHRGWQLLQAVDFGPACPQPV-------RYTGATKGIMDMDEDCL 235

  Fly   129 YLNVYVKDLQPD------KLRPVMVWIYGGGYQVGEASRDMYSPDFFMS-KDVVIVTVAYRLGAL 186
            |||||    .|.      :..||||:|:||.:..|  :.:::......| .|||:||:.||||||
  Fly   236 YLNVY----SPKTGAGVAQKYPVMVYIHGGEFIRG--ASNLFQGHILASFYDVVVVTLNYRLGAL 294

  Fly   187 GFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEG 251
            ||||..|.  |.|||.|:.||.||||||..|||.|.||.|:|||||..|||||...|.::|||..
  Fly   295 GFLSTGDE--NSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRN 357

  Fly   252 LIHKAIVMSGSVLCPWTQPPRNNWAYRLAQKLGYTGDNKDKAIFEFLRSM--SGGEIVKATAT-- 312
            ::.:.|..|||.|..|.          |.|. .|...|..:.:.:.|...  |..::|....|
  Fly   358 IVRRVIAQSGSALADWA----------LIQD-KYRAQNTSRVLGQLLGCSIESSWKLVNCLRTGR 411

  Fly   313 ---VLSNDEKHHRI-LFAFGPVVEPYTT-------------EHTVVAKQPHELMQ-NSWSHRIPM 359
               .|.|.|...:: .|.:|||::...|             :...:.:.|..|:: ..::..|..
  Fly   412 SFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQY 476

  Fly   360 MFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLP-SDL-GLNLDPKLRE-----NYGLQLKKAY- 416
            |.|.|:.|...|             |...::|.| .:| |...|.|:||     ||.|.....|
  Fly   477 MTGVTTQEAAFF-------------VAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNPNGVYE 528

  Fly   417 -------FGDEPCNQA-------NMMKFLELCSYREFWHPIYRAALNR----VRQSSAPTYLY-- 461
                   |..:|.|..       ||:..|           .|||.:::    :.:...|.|:|
  Fly   529 AIKYIYTFWPDPNNNTIIRDQYINMLSDL-----------YYRAPVDQMVKLMLEQKVPVYMYVL 582

  Fly   462 -------------RFDHDSKLCNAIRIVLCG-------------HQMRGVCHGDDLCYIFHSMLS 500
                         ::.||.:     |..|.|             |..|.:...:|      ..:|
  Fly   583 NTTVEALNLPQWRKYPHDIE-----RYFLTGAPFMDTEFFPKKEHLQRNMWTDND------RNMS 636

  Fly   501 HQSAPDSPEHKVITGMVDVWTSFAAHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPEL 565
            |             ..:..:|:||.:|:|..:.:..:.|..... ...:.|||...:....|...
  Fly   637 H-------------FFMQTYTNFARYGNPTPQQVLGMHFQRAYQ-GEIRYLNINTTYNSSILLNY 687

  Fly   566 QKIEPVWNSFYAP 578
            ::.|..:.:.|.|
  Fly   688 RQTECAFWTQYLP 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	156/560 (28%)
		Aes	<132..>279	CDD:223730	68/153 (44%)
Gli	NP_476602.1	COesterase	134..695	CDD:278561	161/591 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440436
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740