Protein Alignment alpha-Est10 and Nlg2

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_523496.1
• Gene: Nlg2 / 33962
• FlyBaseID: FBgn0031866
• Length: 1248
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 147/570 - (25%)
• Similarity: 229/570 - (40%)
• Gaps: 119/570 - (20%)

  Fly    49 SVIKTKSGPVRG--VKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWD--QELDCTSPA- 108
            :.:|||.|.:||  |:.:.:    ..:|..||:|.||||.|||..|.....|.  :..|..||.
  Fly   183 NTVKTKYGLLRGIVVRSSPL----VEAFLGIPYASPPVGSLRFMPPITPSTWKTVRSADRFSPVC 243

  Fly   109 ---------------DKPLQTHMFFRKYA-----GSEDCLYLNVYV-----------KDL--QPD 140
                           :.|.......|:..     .||||||||:||           .|.  :|.
  Fly   244 PQNIPIPPNGPEALLEVPRARLAQLRRLLPLLKNQSEDCLYLNIYVPYETRRQRRNTDDTTGEPK 308

  Fly   141 KLRPVMVWIYGGGYQVGEASRDMY-SPDFFMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGL 204
            .....:|:|:|..|...  |.:.| ..:.....:|::||:.:|||..|||.....: :..||.||
  Fly   309 TKLSTVVFIHGESYDWN--SGNPYDGSELAAHGNVIVVTINFRLGIFGFLKTGGKE-SAQGNFGL 370

  Fly   205 KDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQ 269
            .|.:..|.|:::|:.|||||..:|||.|...|....:.|.:||....||.:.:::|||.|.||.
  Fly   371 MDLVAGLHWLKENLPAFGGDPQSITLLGYGTGAVLANILVVSPVASDLIQRTVLVSGSALSPWA- 434

  Fly   270 PPRNNWAY---RLAQKLGYTGDNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVV 331
             .:.|..:   |:|::.|..||.....:...||:       |:.|.:|:....|.|.|..|.|.|
  Fly   435 -IQKNPLFVKRRVAEQTGCHGDMLYDDLAPCLRT-------KSVAELLAVKVDHPRFLVGFAPFV 491

  Fly   332 EPYTTEHTVVAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPA--TLDEVGNCKNLLPS 394
                 :.||::...:.|    .|..:|:.....|..| :.|....:|..  .|..|.:..:|...
  Fly   492 -----DGTVISPGANPL----GSTTLPLGSAIVSTSG-IEYANFPKRDLIFCLTSVESYLDLSAQ 546

  Fly   395 DL--GLN-------LDPKLRENYGLQLKKAY------FGD------EPCNQANMMKFLELCSYRE 438
            ||  |.|       |...:|.|:...|.:.:      :.|      .|.:..:..  |:..|...
  Fly   547 DLEFGFNETRRDRILRTFVRNNFHYHLNEIFAVLKNEYTDWEKAIRNPLSSRDAT--LQFLSDGH 609

  Fly   439 FWHPIYRAA-LNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQ 502
            ...|:.:.. ::.:|...|  |...|.|.:       |.....|..|...|:|:.:..
  Fly   610 TASPLIKLGYMHSLRGGRA--YFLHFKHKT-------IEEEYPQRSGSVRGEDVPFWL------- 658

  Fly   503 SAPDSP---------EHKVITGMVDVWTSFAAHGDPNCESIKSLKFAPIE 543
            ..|.||         |.::...|:...::||..|:||..:.||:...|.|
  Fly   659 GLPMSPLFPHNYTTQERQIGRLMLRYLSNFAKTGNPNQSTAKSVLPNPNE 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	143/558 (26%)
Nlg2	NP_523496.1	COesterase	182..729	CDD:395084	147/570 (26%)