Protein Alignment alpha-Est10 and Ces4a

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_666325.2
• Gene: Ces4a / 234677
• MGIID: 2384581
• Length: 563
• Species: Mus musculus
• Alignment Length: 507
• Identity: 169/507 - (33%)
• Similarity: 239/507 - (47%)
• Gaps: 48/507 - (9%)

  Fly    53 TKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSPADKPLQ---- 113
            ||.|.::| |:..:.......|..|||:|||||..||..||...||:...|.|:.....||
Mouse    38 TKHGILQG-KQVHVGDTPIQVFLGIPFSKPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWG 101

  Fly   114 --------THMFFRKYAGSEDCLYLNVYVKDLQPD-KLRPVMVWIYGGGYQVGEASRDMYSPDFF 169
                    |...::....||||||||||...|.|. .|.|||||..||.:..|.||  .|.....
Mouse   102 QILSMYLNTRKQYKWLHFSEDCLYLNVYAPVLAPGAPLLPVMVWFPGGAFLAGSAS--TYEGSEL 164

  Fly   170 MSK-DVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGE 233
            .:: .||:|.:.||||.|||.|..:.  :..||.||.|||.||||||:||||||||.:::||||:
Mouse   165 AARGKVVLVFLQYRLGILGFFSTGNS--HARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQ 227

  Fly   234 SAGGASTHFLALSPQTEGLIHKAIVMSG-SVLCPWTQPPRNNWAYRLAQKLGYTGDNKDKAIFEF 297
            |||..|...|.:||..:||.|:||..|| :||..:..|.....|.::|...| ...|..|.:.|.
Mouse   228 SAGAMSVSGLMVSPLAQGLFHQAISQSGTAVLKAFITPDPLTSAKKIAHLAG-CDHNSTKVMVEC 291

  Fly   298 LRSMSGGEIV---KATATVLSNDEKHHR-ILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIP 358
            |||:|..|:.   |..:...:|..|..: |::...|||     :..|..:.|..|:.......:|
Mouse   292 LRSLSAEEVTLVSKRMSFFQANSHKDPKEIVWFLSPVV-----DGVVFPEDPVVLLTRGQVKPVP 351

  Fly   359 MMFG--GTSFE-GLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYGLQLKKAYFGDE 420
            .:.|  ...|| .|.|..::......:::....|.|...::.||:   .:|...: :.:.|..|.
Mouse   352 YLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKILWSFNVLLNI---TKEQVPV-VAREYLNDA 412

  Fly   421 PCNQANMM---KFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQM 482
            ..|....|   :.::|.....|.:...:||... |.:.:|.|||.|.|.:.....|:      ..
Mouse   413 ISNHDWKMFRNRLIDLIGDATFVYATLQAARYH-RDAGSPVYLYEFKHHASSGIIIK------PY 470

  Fly   483 RGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDVWTSFAAHGDPNCESI 534
            .|..|||:|.|:|.|..|..|:. ..|.:....|:..|.:||..|:||.|.:
Mouse   471 NGADHGDELSYLFGSPFSKGSSA-GEEKEFSLQMMKYWANFAHTGNPNGEKL 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	169/507 (33%)
		Aes	<132..>279	CDD:223730	70/149 (47%)
Ces4a	NP_666325.2	COesterase	30..554	CDD:278561	169/507 (33%)
		Aes	<128..>272	CDD:223730	69/147 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832846
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.740