Protein Alignment alpha-Est10 and Ces2e

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_766347.1
• Gene: Ces2e / 234673
• MGIID: 2443170
• Length: 559
• Species: Mus musculus
• Alignment Length: 567
• Identity: 176/567 - (31%)
• Similarity: 250/567 - (44%)
• Gaps: 95/567 - (16%)

  Fly    53 TKSGPVRG----VKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSPADKPLQ 113
            |.:|.|||    ||...|   :..:|..|||||||||.|||..|||.|||....|.||..:..||
Mouse    36 THTGQVRGSLVHVKDTDI---AVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSHPNMCLQ 97

  Fly   114 T------------HMFFRKYAGSEDCLYLNVYV-KDLQPDKLRPVMVWIYGGGYQVGEASRDMYS 165
            .            ::.....:.||||||||:|| .........||||||:||...||.||  ||.
Mouse    98 NDNLMGSEDLKMMNLILPPISMSEDCLYLNIYVPAHAHEGSNLPVMVWIHGGALTVGMAS--MYD 160

  Fly   166 PDFF-MSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNIT 229
            .... .::|||:|.:.||||.|||.|..|.  :..||.|..||:.|||||||||..|||:.:.:|
Mouse   161 GSMLAATEDVVVVAIQYRLGVLGFFSTGDQ--HAKGNWGYLDQVAALRWVQQNIVHFGGNPDRVT 223

  Fly   230 LFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNNWAYRLAQKLGYTGDNKDKAI 294
            :|||||||.|.....:||.::||.|.||:.||..:.|......:...:|:
Mouse   224 IFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVAVLPDLISSSSEMVHRI--------------- 273

  Fly   295 FEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPV--VEPYTTEHTVVAKQPHELMQNSWSHRI 357
               :.::||...|.:...:.....|:...:.|...|  :.|...:...:.|.|.|||.:...|.:
Mouse   274 ---VANLSGCAAVNSETLMCCLRGKNEAEMLAINKVFKIIPGVVDGEFLPKHPQELMASKDFHPV 335

  Fly   358 PMMFGGTSFEGLLFYP----------EVSRR--PATLDEVGNCKNLLPSDLGLNLDPKLRENYGL 410
            |.:.|..:.|.....|          |::|:  ||.|.... .|.:||.:.| :|
Mouse   336 PSIIGINNDEYGWILPTIMDPAQKIEEITRKTLPAVLKSTA-LKMMLPPECG-DL---------- 388

  Fly   411 QLKKAYFGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRI 475
             |.:.|.||....:....:|.|:.....|..|..:.|  ..::|.||.|.|.|.|........|.
Mouse   389 -LMEEYMGDTEDPETLQAQFREMKGDFMFVIPALQVA--HFQRSHAPVYFYEFQHRPSFFKDFRP 450

  Fly   476 VLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVIT-GMVDVWTSFAAHGDPNCESIKSLKF 539
            ......     |||::..:|.....:...|.:.|.:.:: .::..|.:||.||:||.|   .|.:
Mouse   451 PYVKAD-----HGDEIFLVFGYQFGNIKLPYTEEEEQLSRRIMKYWANFARHGNPNSE---GLPY 507

  Fly   540 API-ENVTNFKCLNIGD-----------QFEVMALPELQKIEPVWNS 574
            .|: ::...:..|:|..           ||....||  |||:.:..|
Mouse   508 WPVMDHDEQYLQLDIQPSVGRALKARRLQFWTKTLP--QKIQELKGS 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	163/512 (32%)
Ces2e	NP_766347.1	COesterase	30..538	CDD:395084	169/549 (31%)