Protein Alignment alpha-Est10 and Nlgn1

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_006535478.1
• Gene: Nlgn1 / 192167
• MGIID: 2179435
• Length: 863
• Species: Mus musculus
• Alignment Length: 651
• Identity: 174/651 - (26%)
• Similarity: 251/651 - (38%)
• Gaps: 180/651 - (27%)

  Fly    50 VIKTKSGPVRGVKR---NTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSPA--- 108
            ::.|..|.:||:|:   |.|. |....|..:|:|.||.|:.||:.||...||....:.|..|
Mouse    54 LVTTNFGKIRGIKKELNNEIL-GPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVC 117

  Fly   109 -----DKPLQTHMF----------FRKYA--GSEDCLYLNVYV--KDL---------QPDKL--- 142
                 |..|...|.          ...|.  .||||||||:||  :|:         :|.|.
Mouse   118 PQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICR 182

  Fly   143 ------------------------------RPVMVWIYGGGYQVGEASRDMYSPDFFMS-KDVVI 176
                                          :||||:|:||.|.  |.:.::|......| .:|::
Mouse   183 KGGPLTKKHTDDLGDNDGAEDEDIRDSGGPKPVMVYIHGGSYM--EGTGNLYDGSVLASYGNVIV 245

  Fly   177 VTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTH 241
            :||.||||.|||||..|..  ..||.||.|.|.||||..:||..||||...||:||..|||:..:
Mouse   246 ITVNYRLGVLGFLSTGDQA--AKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVN 308

  Fly   242 FLAL---------SPQTEGLIHKAIVMSGSVLCPWT---QPPRNNWAYRLAQKLGYTGDNKDKAI 294
            .|.|         |..|:||..:||..||:.|..|.   ||.:  :|..||.|:|....:..:.:
Mouse   309 LLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAK--YARILATKVGCNVSDTVELV 371

  Fly   295 FEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPM 359
             |.|:.....|:|       ..|.:..|...|||||:     :..|:...|..||:........:
Mouse   372 -ECLQKKPYKELV-------DQDVQPARYHIAFGPVI-----DGDVIPDDPQILMEQGEFLNYDI 423

  Fly   360 MFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLD----------------PK----L 404
            |.|....|||.|                .:|::.||.|::..                |:    |
Mouse   424 MLGVNQGEGLKF----------------VENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVL 472

  Fly   405 RENYGLQLKKAY--FGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDS 467
            ||.    :|..|  :.|....:......|.|.:..::..|.. |..:......:|||.|.|.|.
Mouse   473 RET----IKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAV-ATADLHSNFGSPTYFYAFYHH- 531

  Fly   468 KLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPD-------SPEHKVITGMV-DVWTSFA 524
              |...::    .......|||::.|:....:   ..|.       |....:::.:| ..||:||
Mouse   532 --CQTDQV----PAWADAAHGDEVPYVLGIPM---IGPTELFPCNFSKNDVMLSAVVMTYWTNFA 587

  Fly   525 AHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPELQK---------IEPVWNSFYAPNK 580
            ..||||....:..||  |....|        :||.:|.....:         ::|.....|..||
Mouse   588 KTGDPNQPVPQDTKF--IHTKPN--------RFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANK 642

  Fly   581 L 581
            :
Mouse   643 V 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	165/601 (27%)
		Aes	<132..>279	CDD:223730	67/203 (33%)
Nlgn1	XP_006535478.1	COesterase	53..646	CDD:365897	174/651 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740