Protein Alignment alpha-Est10 and cest-28

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 509
• Identity: 158/509 - (31%)
• Similarity: 236/509 - (46%)
• Gaps: 77/509 - (15%)

  Fly    56 GPVRG----VKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTS-----PADKP 111
            ||::|    :...|:.|     :..||||||.|   |||.||....|::..|||.     |...|
 Worm    22 GPIQGNVYRIGDKTVDG-----YLGIPFAKPLV---RFKKPEPAGTWEEVRDCTKYGPRCPQSGP 78

  Fly   112 LQTHMFFRK--YAGSEDCLYLNVYVK---DLQPDKLRPVMVWIYGGGYQVGEASRDMYSPDFFMS 171
            ....:.|:|  .....:||.|||:.|   ....:|.|||||:|:||||:. .||||..  |:.::
 Worm    79 FAEAINFQKDDIPDEANCLTLNVFSKISDSKNFNKTRPVMVYIHGGGYEC-SASRDYC--DYSVA 140

  Fly   172 -----KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLF 231
                 ||||:||:.||:|.|||.:..|..  .|||..|.|..:.|.|:|::||:||||..|||:|
 Worm   141 GTLPLKDVVVVTLNYRVGILGFFTTGDTV--CPGNFALWDLTLGLNWIQKHIESFGGDPGNITIF 203

  Fly   232 GESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNNWA---YRLAQKLGYTGDNKDKA 293
            |:|||.|....|||||.:..|.::.|||||..||.:.....|:.|   |..|:.|||.|.| .:.
 Worm   204 GQSAGAACVDLLALSPHSRDLFNRVIVMSGGALCEYAVRTANSQAKVCYEFARHLGYDGTN-SQT 267

  Fly   294 IFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVE----PYTTEHTVVAKQPHELMQNSWS 354
            :|.:::|....||.|     ::..:.....:.|:.|.::    |.:.:...:.....::|.....
 Worm   268 LFNWMKSKPLEEIEK-----MNGFQVPASGILAWTPNLDDDFFPKSLDELRIGAPKKDIMMGFAE 327

  Fly   355 HRIPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDP---KLRENYGLQLKKAY 416
            |.      |..||.|:..|........|    ........|.|.:.:.   |:.|.|...::..
 Worm   328 HE------GLFFEFLIKDPTPPLEALKL----YVNEYYKKDTGDHFEATRNKIIEFYSRNVEDT- 381

  Fly   417 FGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQ 481
              ||...:..::.|:   ....|...::..|.|.::..: ..:||.||:    ||....   |:|
 Worm   382 --DEKSTKERLIDFV---GDALFTAGVFDNAKNCLKHGN-NVWLYIFDY----CNPSGF---GNQ 433

  Fly   482 ---MRGVC--HGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDVWTSFAAHGDPN 530
               |..|.  |..||.|:....|.....|...|||:|..|..::::||.:|:||
 Worm   434 EEFMTFVAPTHCTDLRYVLGEGLYSDFQPTEEEHKMIEKMTTIYSNFAKYGNPN 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	158/509 (31%)
cest-28	NP_504691.2	COesterase	17..526	CDD:395084	158/509 (31%)