Protein Alignment alpha-Est10 and cest-8

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001359583.1
• Gene: cest-8 / 182818
• WormBaseID: WBGene00007691
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 527
• Identity: 120/527 - (22%)
• Similarity: 213/527 - (40%)
• Gaps: 112/527 - (21%)

  Fly    35 SFKYEQRKLSTAIYSVIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWD 99
            |..||.:.|     .:|.|..|.:||:...:......|:|:.:||||||:|:|||..|:.::.||
 Worm    10 SLLYEFQTL-----KIINTSYGKLRGMAEWSDDANHKFTFKSVPFAKPPIGNLRFAPPQKLDHWD 69

  Fly   100 QELD-------CTSPADKPLQTHMFFRKYAGSEDCLYLNVYVKDLQPDKLRPVMVWIYGGGYQVG 157
            ..||       |.|.:....|:::       :|||||:|::..:........|:|:.:||.|...
 Worm    70 GILDASVYSAACMSNSTLTTQSYV-------NEDCLYINIFTSEKCLKSKCSVIVYFHGGAYNTE 127

  Fly   158 EAS--RDMYSPDFFMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEA 220
            .|:  .|.:..|.::.:||:.|..|.|||..|.|.. .|...:..|..:.|.|:||.:|...|..
 Worm   128 SATMFSDRFILDRYVHEDVIFVIPAVRLGVFGQLYF-GPNAYLTENLFMFDAILALDFVHNEISN 191

  Fly   221 FGGDSNNITLFGESAGGASTHFLALSPQTE---GLIHKAIVMSGSVLCPWTQPPRNNWAYRLAQK 282
            ||||...:|:.|.|:||.....|..|...:   .|..:.|::|.:.:..:.....:| ::.:.:|
 Worm   192 FGGDPEKVTIMGHSSGGTLVEALGFSSMVDPELKLFQQMIMLSSTGMFGFDDLVIDN-SFTIVEK 255

  Fly   283 LG-YTGDNKDK------AIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTV 340
            || :.|..:::      ...:.:|.:.|.||::....:...|:...:.|....|.:        :
 Worm   256 LGCFNGTKEERNTVNVAETLDCMRHIDGYEILRVQQKMELMDQLSFKYLLRGAPFM--------L 312

  Fly   341 VAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRR----PATLDEVGNCKNLLPSDLGLNLD 401
            :.....:|.:|:....  .:||.|..|   |: :|:.:    ..|..:..|     |..:..|.|
 Worm   313 LNGNIADLKKNTSPRN--AIFGTTEHE---FF-DVTEKYLYITVTFLDYEN-----PVAVARNYD 366

  Fly   402 PKLRENYGLQLKKAYFGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHD 466
            .:|.:|    ::....||    .|.:......|:          ||:   ..:.|..:|:.....
 Worm   367 GRLMKN----METMITGD----SAAIFVSTATCA----------AAM---ANAGADVFLFETRQS 410

  Fly   467 SKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDV--------WTSF 523
            ..:                 |..|:.|...:..:|....|          :|:        .|:|
 Worm   411 YSV-----------------HVSDMQYFIGNHCAHNRTID----------IDILDSFYSKLLTNF 448

  Fly   524 AAHGDPN 530
            ..||.|:
 Worm   449 TKHGKPS 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	116/513 (23%)
		Aes	<132..>279	CDD:223730	40/151 (26%)
cest-8	NP_001359583.1	Abhydrolase	19..495	CDD:389770	116/513 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157151
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740