Protein Alignment alpha-Est10 and cest-13

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_741921.1
• Gene: cest-13 / 181493
• WormBaseID: WBGene00010116
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 575
• Identity: 148/575 - (25%)
• Similarity: 252/575 - (43%)
• Gaps: 97/575 - (16%)

  Fly    43 LSTAIYSV-IKTKSG--PVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDC 104
            |:...|.| ::|.:|  .:||::..  :|   .||..|.:|:||||..||.|...::|... ::.
 Worm    18 LADPTYDVTVQTPNGSATIRGIQHT--YG---TSFRGIRYAQPPVGLFRFGAARRLDPVGL-VEA 76

  Fly   105 TSPADKPLQ-----THMFFRKYAGSEDCLYLNVYVKD--LQPDKLRPVMVWIYGGGYQV--GEAS 160
            .:..:..:|     :|         ||||::|||..:  .|..|| ||.|:|:|||:..  |...
 Worm    77 QAYGNICVQGDGRTSH---------EDCLFINVYTPNNVTQASKL-PVYVYIHGGGFVEGGGNMG 131

  Fly   161 RDMYSPDFFMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDS 225
            ..:| |:......:|:|::.||||..||.|  ..|:..|||..:.|.|.||.|||:.|..||||.
 Worm   132 AGIY-PNLVNKGPIVMVSINYRLGPFGFFS--TRQMTAPGNWAISDWIEALNWVQRYISFFGGDP 193

  Fly   226 NNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGS----VLCPWTQPPRNNWAYRLAQKLG-Y 285
            |.:|:.|:|:|..:...|.|:|..:.|..::|..|||    .:..:::..|:. :.:|:.||| .
 Worm   194 NRVTIGGQSSGAEAVSTLTLTPLAKNLFKQSIHESGSAFGAAVMSYSEKTRST-SKQLSIKLGCA 257

  Fly   286 TGDNKDK-----AIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVE--PYTT---EHTV 340
            |.|..|.     .|...||:::..:||.|     .|....||:.::   :|:  .|.|   |:..
 Worm   258 TSDQWDNGQSFGTILTCLRNVTYDKIVAA-----DNSLPGHRMKWS---IVQDNKYLTQRLEYLA 314

  Fly   341 VAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLR 405
            :.:.|.:          .::.|....|.|.:  |::.....::...|..:.:..||..:.:....
 Worm   315 LQRDPKK----------NVLIGDVHDEWLGW--EMNNVLHNINSSHNTAHQMRDDLSGSYEMTYW 367

  Fly   406 ENYGLQLKKA---YFGDEPCNQANMMKF----LELCSYREFWHPIYR-AALNRVRQSSAPTYLYR 462
            :|....|..|   |..::.....|..::    ::|.|...|..|..| ||..:..:::  .|||.
 Worm   368 DNKQSVLVAADNKYINNQGWTDDNHREWEARRIQLWSEMVFIGPTLRDAAYFQYMKNN--VYLYS 430

  Fly   463 FDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITG-MVDVWTSFAAH 526
            .|..|.  .|:.:| .....||..|..:|.|||.:  |......:.:.:::.. ....|.:|...
 Worm   431 LDWLSP--PALPLV-TDPLFRGCEHTWELQYIFST--SCNGFTCTAQDEILRNYFTTTWLNFIIG 490

  Fly   527 GDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPELQKIEPVWNSFYAPNKL 581
            |:|          .|..:...||.|.:......::.....|::|    .|.|:.:
 Worm   491 GNP----------TPAGSPLPFKWLAMDSTNRFLSFSPNPKMQP----HYHPDSM 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	138/519 (27%)
cest-13	NP_741921.1	alpha/beta hydrolases	24..526	CDD:473884	144/562 (26%)