Protein Alignment alpha-Est10 and cest-3

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 132/515 - (25%)
• Similarity: 207/515 - (40%)
• Gaps: 115/515 - (22%)

  Fly    50 VIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCT--SP---AD 109
            :|.|..|.:.|...|.    ....|:.:||||||:|.|||..||...||....:.|  ||   ::
 Worm    23 IISTTYGKLEGKTVNV----DQHMFKNVPFAKPPLGKLRFSLPEWTNPWKNIRNATEYSPSCFSN 83

  Fly   110 KPLQTHMFFRKYAGSEDCLYLNVYVKD-LQPDKLRPVMVWIYGGGYQVGEASR--DMYSPDFFMS 171
            ..::|...|  :..|||||||||:..: ....|....:|:.:|||..:..|.:  |.:..:.::.
 Worm    84 SSMRTDSNF--FPMSEDCLYLNVFTNEYCLKSKNCSTVVYYHGGGINMDSAVQFNDTFILERYVK 146

  Fly   172 KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAG 236
            ::||.:..|||||..|.|......| ||.|..:.|..:|||::.|.|..|||..::|.|.|.|||
 Worm   147 ENVVFIIPAYRLGIFGLLYFGSNNL-VPQNLAIHDCELALRFIHQEISNFGGHKDDINLMGHSAG 210

  Fly   237 -------GASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPP----RNNWAYRLAQKLGYTGDN- 289
                   |.|.|   :.|..: ||::.||:|.   .|....|    :|  .|..|:::|....|
 Worm   211 AHISLIFGFSRH---IDPDHK-LINRIIVLSP---VPSYDMPELLIKN--CYDFAERVGCYKRNV 266

  Fly   290 --KDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNS 352
              :|..|.:.||......:: :...::.||..:.....|..|.:  |..|.....|:
 Worm   267 TARDTEIVKCLRKKDARGLM-SMQRLMENDRLYFWNFLAGEPFM--YRDESIADFKE-------- 320

  Fly   353 WSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEV--GNCKNLLPSDLGLNLDPKLREN-YGLQLKK 414
            ::.:..|:.|.                 |:|||  ...|...|:..|..:|   .|| |.:..|.
 Worm   321 YAVKRDMLIGN-----------------TVDEVKWKRLKKENPAIAGSFMD---WENPYEVAHKF 365

  Fly   415 AYFGDE-PCNQANMMKFLELCSYREFWHPIY-RAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVL 477
            .::.|. |.|.          :|..|...|: ..|.....|::|...:|.|..:.:..:
 Worm   366 NFYHDSAPVNS----------TYESFTQGIFVSTATYAEAQANAGGTVYLFQSNQQPSS------ 414

  Fly   478 CGHQMRGVCHGDDLCYI-------FHSMLSHQSAPDSPEHKVITGMVDVWTSFAAHGDPN 530
                     |..|:.|.       :|:  |.....|:...|:|       .:|...|.|:
 Worm   415 ---------HVSDMQYFVGTHREDYHT--SDMDIMDTFYSKMI-------VNFTKFGSPS 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	132/515 (26%)
cest-3	NP_510042.2	alpha/beta hydrolases	21..496	CDD:473884	132/515 (26%)