Protein Alignment alpha-Est10 and cest-16

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 608
• Identity: 161/608 - (26%)
• Similarity: 243/608 - (39%)
• Gaps: 146/608 - (24%)

  Fly    24 FTNGDFIQQVISFKYEQRKLSTAIYSVIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLR 88
            :.||..:::..|...||               |.|||...| |.|.....|..:|:|:||:|:||
 Worm    14 WANGQLLEKSRSVWVEQ---------------GLVRGNIYN-IDGKHIQIFRGVPYAEPPIGELR 62

  Fly    89 FKAPEAVEPWDQELDCTSPADKPLQTHMFFR--KYA------GSEDCLYLNV---YVKDLQPDKL 142
            ||.|.....|.|||.........||...|.:  |:|      .|||||||||   |..| ...|.
 Worm    63 FKPPVKKTRWHQELPAVEYGPPCLQFMDFHKNDKFAKTNMDRQSEDCLYLNVFSPYDTD-DESKT 126

  Fly   143 RPVMVWIYGGGYQVGEASRDMYSPDF------FMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGN 201
            .|::|||:||.:..|.|...:   |.      .:||.:..|::.||||.|||::..:.. .:.||
 Worm   127 YPILVWIHGGSFLAGSADTGI---DMEVIAANIVSKGIAFVSINYRLGPLGFMNYQNGD-KLEGN 187

  Fly   202 AGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCP 266
            .|:.|.:|||:|:|.||:.|.||...:|:.|||||||::..|||||:|.||:|:||:||||.:..
 Worm   188 FGIWDMVMALQWIQSNIKQFNGDPTKVTVMGESAGGAASSLLALSPKTSGLLHQAIIMSGSSMAG 252

  Fly   267 WTQPPRNNWAYRLAQKLGY---------------TGDNKDKAIFEFLRS---------------- 300
            |.....:..||.:...:.|               .||.........:||
 Worm   253 WAIHRHSQPAYSVDNLVAYFRCEKWINEDDTKEVVGDEYQHLTHSVIRSALCNYQNVKINCLTDD 317

  Fly   301 MSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNS------------- 352
            |:..:.:......|:......|...|....|.....:..:|......|::|:
 Worm   318 MTQMDKMNCLRKELNFSSPLFRKALAAELGVSKMVVDGDLVPSSGVSLVRNNARIPIMTGVARKE 382

  Fly   353 WSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYGLQLKKAYF 417
            |.|:..|.:.....:||       :|....::|   ..::.:........|| .|..:||
 Worm   383 WGHKKAMFYNMHQRDGL-------KRSDVEEQV---YRIIDNSFHETASEKL-ANSTVQL----- 431

  Fly   418 GDEPCNQANMMKFLE-----------------LCSYREFWHPIYRAALNRVRQSSAPTYLYRFDH 465
                ...|.::::||                 |.|..||..|..|.....| ....|.|||.||:
 Worm   432 ----IANATIVRYLETPNNEFIADQVVGALQKLESDIEFVAPCEREVAAYV-DKGVPVYLYSFDY 491

  Fly   466 --DSKLCNAIRIV--LCGHQ-------------MRGVCHGDDLCYIF------HSMLSHQSAPDS 507
              .|.:..:.|.:  |.|.:             .:...||.|..:||      :..:|..:..:.
 Worm   492 VPKSPILESERKIYSLFGTKPVEMKRTEKSEILEKAAFHGLDHAFIFSKGYSSNFEISPYTKREE 556

  Fly   508 PEHKVITGMVDVWTSFAAHGDPN 530
            ...|::..|:   |:|..:|||:
 Worm   557 TMSKILCTML---TNFVKNGDPS 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	156/583 (27%)
		Aes	<132..>279	CDD:223730	63/155 (41%)
cest-16	NP_741812.2	Abhydrolase	25..608	CDD:389770	159/597 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910