Protein Alignment alpha-Est10 and cest-2.3

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_506510.2
• Gene: cest-2.3 / 179918
• WormBaseID: WBGene00013873
• Length: 665
• Species: Caenorhabditis elegans
• Alignment Length: 588
• Identity: 140/588 - (23%)
• Similarity: 240/588 - (40%)
• Gaps: 118/588 - (20%)

  Fly    33 VISFKYEQRKLSTAIYSVIKTKSGPVRGVKRNTIWG--GSYFS--FEKIPFAKPPVGDLRFKAPE 93
            ::.:.|....:..:|.:.|:..:|.:.|...|..:.  |:..:  |..||:.:||:|:|||:.|.
 Worm     2 ILQYLYFAVLIHLSISTRIQLSTGTIEGKILNATYSPFGNQTATVFLGIPYVEPPIGELRFRKPR 66

  Fly    94 AVEPWDQELDCT--SPADKPLQTHMFFRKYAG--SEDCLYLNVYVKD--LQPDKLRPVMVWIYGG 152
            .::.|:..|:..  .||........|...:.|  ||||||.||:...  || :|...||:.::||
 Worm    67 LLKSWEGVLETKDYKPACMSYWRKTFKNGFVGEISEDCLYANVFTNQYCLQ-NKNCSVMIVVHGG 130

  Fly   153 GY--QVGEASRDMYSPDFFMS------KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIM 209
            ..  :.|.|    :.|:.|::      :::|:||..||||..||...:....:.  |..:.|.:.
 Worm   131 RLVCESGSA----FKPEIFINNFVGQDRNIVVVTFNYRLGVFGFGVFNGETGDT--NVAMYDMLE 189

  Fly   210 ALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSG------------- 261
            |::||::.|:.|||:.:.||:.|.|||.........|..::||:|:.||||.
 Worm   190 AVKWVRKEIDQFGGNKDRITMAGHSAGAGLIVDFTSSTLSKGLLHQQIVMSAPLQDISKSANFKG 254

  Fly   262 ------SVLC-PWTQPPRNNWAYRLAQKLGYTGDNKDKAIFEFLRSMSGGEIVKATATVLSNDEK 319
                  :|.| |      ..:.:|   ||..|..||   .:..|::.|..:::.|..::..|.
 Worm   255 MTIVAQNVGCIP------KEYGFR---KLSKTQINK---TYLCLQNKSAQDLLHAQLSMQQNS-- 305

  Fly   320 HHRILFAFG-PVVE-PYTTEHTVVAKQPHELMQNSWSHRIPMMFGGTSFE--GLLFY--PEVSRR 378
                .|.|| |.|: .:.|::      |..|...:..:.|....|.|:.|  ..|:.  |:..|.
 Worm   306 ----TFYFGSPRVDGDFITDY------PDNLFNFNTIYPINTFIGTTTGELRDSLYITDPKNDRI 360

  Fly   379 PATLDEVGNCKNLLPSDLGLNLDPKLRE------NYGLQLKKAYFGDEPCNQANMMKFLELCSYR 437
            ...|     .||:. ..:|..|..|..|      ||......|.|               |....
 Worm   361 KEQL-----LKNMC-EHVGYELFEKPEEFTKKCGNYYKNGTDAQF---------------LSDDM 404

  Fly   438 EFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQ 502
            ||:....:.| |..:::::..::|.:|:.. ...|....|   :.....|.:||.|.|.:.....
 Worm   405 EFYSGAIKVA-NAHKRANSKVFMYSYDYKG-AGTAFHKYL---EAPSPHHSEDLIYTFGTSRGPF 464

  Fly   503 SAPDSPEHKVITGMVDVWTSFAAHGDPNCESIKSLK--------FAPIENVTNFKCLNIGDQFEV 559
            .|.|....::.:||:   .:|....||:....:..:        :..|:...||....:.|.:..
 Worm   465 VAKDYVIERIYSGML---ANFINFEDPSPSKTQQWRQYTQEKREYFLIDFDKNFTMPGMKDHYYT 526

  Fly   560 MAL 562
            .||
 Worm   527 RAL 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	132/533 (25%)
cest-2.3	NP_506510.2	alpha/beta hydrolases	17..532	CDD:473884	138/573 (24%)