Protein Alignment alpha-Est10 and cest-2.1

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 551
• Identity: 134/551 - (24%)
• Similarity: 233/551 - (42%)
• Gaps: 132/551 - (23%)

  Fly    43 LSTAIYSVIKTK----SGPVRGVKRNTIWG--GSY--FSFEKIPFAKPPVGDLRFKAPEAVEPWD 99
            |||.::..|.|:    :|.:.|....:.:.  |::  ..|..|||.:||.|:|||:.|....|||
 Worm     9 LSTLLHISISTRVQLSTGTIEGKILTSTYSPLGNHTGIGFLGIPFVEPPAGNLRFRKPRPPIPWD 73

  Fly   100 QELD-------CTSPADKPLQTHMFFRKYAG---SEDCLYLNVYVKD-LQPDKLRPVMVWIYGGG 153
            ..|:       |.|.|.|.      ::...|   ||||||.||:... ....|...||:.::||
 Worm    74 GILETKEYKPACMSDAKKT------YKNGVGGPISEDCLYANVFTNQYCMKRKNCSVMIVVHGG- 131

  Fly   154 YQVGEASRDMYSPDFFMS------KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALR 212
             ::...|...::|:..::      :::|:||..||||..||..|:..:.:  .|.|:.|.:.|::
 Worm   132 -RILTESASAFNPEILVNNFVGQGRNIVVVTFNYRLGTFGFGVLNGEKGD--SNVGMFDMLEAVK 193

  Fly   213 WVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNNWAY 277
            |.::.:..|||:.:.:|:.|.||||:.......||.::|::::.|:|||::             |
 Worm   194 WTRKEVHNFGGNKDKLTMVGHSAGGSLVGAFTSSPLSKGMLNQQIIMSGAL-------------Y 245

  Fly   278 R------------LAQKLG----YTGDNK------DKAIFEFLRSMSGGEIVKATATVLSNDEKH 320
            :            :|||.|    ..|..|      ||. :..||::|..|::.|...||.|...:
 Worm   246 QMGKLANFKGMTAMAQKAGCLPEVFGFRKLSQVRIDKT-YSCLRNISAQEVLDAQLWVLQNTTYY 309

  Fly   321 HRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEV 385
            ..:....|..:..|:          .|::.:...|.|..|.|.|:.|        .|.|..::::
 Worm   310 ISVPHIDGEFLLNYS----------DEILASGTIHPINSMIGTTTAE--------LRDPIYINDL 356

  Fly   386 GNC-------KNLLPSDLGLNL--DPKLRENYGLQLKKAY-FGDEPCNQANMMKFLELCSYREFW 440
            .|.       |||. ..:|..|  :|   |.:..:.:|.| .||:....|:.|         ||:
 Worm   357 KNADKKEELLKNLC-EHIGYELYTEP---EEFSRKCQKFYGNGDDAQFLADDM---------EFY 408

  Fly   441 HPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMRGVC------HGDDLCYIFHSML 499
            ....:.| |.....:...::|.:|:..          .|...:...      |.:||.|:|.:..
 Worm   409 DGSIKVA-NAHASKNTKVFMYSYDYKD----------AGPAFKKYAQAPPPHHSEDLIYVFGTSR 462

  Fly   500 SHQSAPDSPEHKVITGMVDVWTSFAAHGDPN 530
            .:.:..|....::.:||   :..|...|:|:
 Worm   463 GNFTEKDYVIEQIYSGM---FADFVNFGNPS 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	131/545 (24%)
		Aes	<132..>279	CDD:223730	40/165 (24%)
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	129/539 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157080
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740