Protein Alignment alpha-Est10 and cest-1.2

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 531
• Identity: 136/531 - (25%)
• Similarity: 231/531 - (43%)
• Gaps: 99/531 - (18%)

  Fly    46 AIYSVIKTKSGPVRGVKRNTIW----GGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELD--- 103
            ||.:.::..:|.:.|.:.|:.:    ..|..:|..||:.:||:|||||:.|...:.|...|:
 Worm    16 AISTKVQLSTGIIEGKQLNSTYSPFGNQSAIAFLGIPYVEPPIGDLRFRKPRPQKTWSGVLETKK 80

  Fly   104 ----CTSPADKPLQTHMFFRKYAG-----SEDCLYLNVYVKD-LQPDKLRPVMVWIYGGGYQVGE 158
                |.|.:.|..       |..|     |||||||||.... ...:|...|::.::||||....
 Worm    81 FKPACMSNSTKTY-------KNGGIGGPISEDCLYLNVLTNQYCLENKNCSVVIIVHGGGYLFES 138

  Fly   159 A---SRDMYSPDFF-MSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIE 219
            |   :.::...:|. ..:::|:||:.||||..||..|:.  .....|.|:.|.:.|::||::.|:
 Worm   139 AATFNHEILVNNFVGQDRNIVVVTINYRLGIFGFGHLNG--FEGDKNVGIFDTLEAVKWVRREIK 201

  Fly   220 AFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNN-------WAY 277
            .|||:.:.|||.|.|||........:||.|:||||:.|||||    |.|...:.:       .|.
 Worm   202 QFGGNKDRITLAGHSAGAGVVAAFTISPLTKGLIHQQIVMSG----PMTNMSKKSNFKGMTAMAE 262

  Fly   278 RL---AQKLGYT--GDNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFG--PVVEPYT 335
            |:   ::|.|:.  .:::.:.::..||.....|::.|...:|.|.      .|.||  ||...:.
 Worm   263 RVGCHSKKYGFNKLPEHEVEQVYSCLRKKPAQELLDAQLWLLQNS------TFYFGAPPVDGEFI 321

  Fly   336 TEHTVVAKQPHELMQNSWSHRIPMMFGGTSFE----GLLF---YPEVSRRPATLDEVGNCKNLLP 393
            |::      |..|........|..:.|.|:.|    |.:.   |.:...:...|      |||.
 Worm   322 TDY------PDNLYSEKSIFSINTLLGTTTRELQDTGYISNSNYSKFETKETFL------KNLC- 373

  Fly   394 SDLGLNLDPKLRENYGLQLKKAYF-GDEPCNQANMMKFLELCSYREFWHPIYRAALNRV---RQS 454
            ..:|:.: .|..|::..:.:|.|. |.:..:.::.|:|             |..|:|..   .:.
 Worm   374 DQIGIEI-YKESEDFSSKCQKWYINGSDSKSLSDDMEF-------------YTQAINLADAHARK 424

  Fly   455 SAPTYLYRFDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDV 519
            ....|:|.:.: |....|.:..:   :::...|.:||.|.|.:.....:..|.....:.:||
 Worm   425 GKKVYMYSYAY-SGAGPAFKKYM---KVKSPHHSEDLIYTFGTHRGVFAPKDYVIEYIYSGM--- 482

  Fly   520 WTSFAAHGDPN 530
            :..|....||:
 Worm   483 FADFINFEDPS 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	134/528 (25%)
cest-1.2	NP_506504.2	COesterase	18..536	CDD:395084	134/529 (25%)