Protein Alignment alpha-Est10 and cest-17

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_505114.1
• Gene: cest-17 / 179198
• WormBaseID: WBGene00019477
• Length: 571
• Species: Caenorhabditis elegans
• Alignment Length: 593
• Identity: 159/593 - (26%)
• Similarity: 241/593 - (40%)
• Gaps: 141/593 - (23%)

  Fly    51 IKTKSGPVRGVK-RNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQ--------ELDCTS 106
            :.|..||:.|.: ::|:.|..|..|..|.:..||....||:.||.||.|..        ...|..
 Worm    24 VTTPYGPIVGFEHKSTVTGSKYHVFLGIRYGNPPDHIYRFQKPEPVEKWPHINHDATHFRASCIP 88

  Fly   107 PADKPLQTHMFFRKYAGSEDCLYLNVYVKDLQPDKLRPVMVWIYGGGYQVGEASRDMY--SPDFF 169
            .....|:..:.:     |||||:||:.......:|..||:|:|:|||:|.|:.|...|  :.|.|
 Worm    89 SLRSELEEQVNY-----SEDCLFLNIVTPPDAKEKKLPVLVFIHGGGFQFGDTSMIGYQKAADNF 148

  Fly   170 MSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGES 234
            :|||::.|::.||||.|||.:..|.:  :|||.||.||.:||:::.:.:..||||.:.|||.|.|
 Worm   149 VSKDIIFVSIQYRLGPLGFFTTGDSE--IPGNMGLWDQTLALQFLHEVLPDFGGDPDRITLAGHS 211

  Fly   235 AGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRN--NWAYRLAQKLGY-TGDNKD----- 291
            ||.||...|..||.::.|..:||.:|||:... :...||  :.:.:||:..|. ..|:|:
 Worm   212 AGAASVSALLYSPHSDHLFSQAIQLSGSIFSE-SNLDRNVVDDSRKLAKAAGCPQEDSKELRDCI 275

  Fly   292 --KAIFEFLRSM-SGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHE------ 347
              :.:.|.|.:| |.||::....|     :|.|..   |.....||..| .:..|.|.:
 Worm   276 EIRTVDELLDAMESIGELLPGPRT-----KKFHPY---FDKDFFPYDIE-KMSRKAPKKRTMQGL 331

  Fly   348 --------------------LMQNSWSH--------------RIPMMFGGTS--FEGLL--FY-- 372
                                :.:.|||.              .:...||..|  |.||:  ||
 Worm   332 VSLESGLSVLYPVKLAKLLGVPKESWSTYSKDNLVDFIRSQVAVEQEFGTASARFSGLVEEFYLS 396

  Fly   373 -PEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYGLQLKKAYFGDEPCNQANMMKFLELCSY 436
             |........|:...|    |.|||..|: |.|.|   ::||..:..|
 Worm   397 GPMTGNSSFYLNAFAN----LLSDLQYNI-PTLHE---VELKLQHGWD----------------- 436

  Fly   437 REFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSH 501
                                 ||||..|:||:......     |.::|..|..:|.|:|:.....
 Worm   437 ---------------------TYLYIIDYDSETTKDPT-----HPIKGPFHASELRYLFNFNGMD 475

  Fly   502 QSAPDSPEHKVITGMVDVWTSFAAHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPELQ 566
            ....:..:.|.....|:...:|...|.|   |.|:|.:..:.....|..|.:.|:..|......:
 Worm   476 TIPFNDKDKKFENYFVNAIVNFINTGTP---STKALLWPAVSKSQPFANLLLNDKPSVQTSFRQE 537

  Fly   567 KIEPVWNS 574
            ..| :|.|
 Worm   538 AYE-LWQS 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	152/559 (27%)
		Aes	<132..>279	CDD:223730	59/150 (39%)
cest-17	NP_505114.1	COesterase	20..542	CDD:278561	157/589 (27%)
		Aes	<109..>225	CDD:223730	50/117 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810