Protein Alignment alpha-Est10 and cest-34

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_001360105.1
• Gene: cest-34 / 179057
• WormBaseID: WBGene00019652
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 161/538 - (29%)
• Similarity: 244/538 - (45%)
• Gaps: 94/538 - (17%)

  Fly    49 SVIKTKSGPVRGVKRNTIWGG--SYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTS----- 106
            :|:.|..|||.|   |....|  ....:..:|:||||.|::||..|...:.|.:..|||.
 Worm    15 TVLNTSCGPVLG---NLYRHGDKEVHGYLGMPYAKPPTGEMRFAKPVPADDWTETRDCTKYGPRC 76

  Fly   107 -PADKPLQTHMFFRKYAGSE-DCLYLNVYVKDLQPDK---LRPVMVWIYGGGYQVGEASRDMYSP 166
             |:.:.|:..||.......| :.|.:||:|...:..:   .|||||:::|||::: .:||:..
 Worm    77 PPSGQGLEKGMFVNPDEPDEANGLSVNVFVPGWESSEYKNARPVMVYVHGGGFEI-SSSREFC-- 138

  Fly   167 DFFMS-----KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSN 226
            |:.:|     |||::||:.||||.|||.:..|..  .|||.||.||.:||:|||::|.:||||.|
 Worm   139 DYSISSTLPMKDVILVTMNYRLGILGFFTTGDEV--CPGNFGLWDQTLALQWVQKHIASFGGDPN 201

  Fly   227 NITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNNWAY---RLAQKLGYTGD 288
            |:||||:|||||....|.|||.:..|..|.:.||||.:|.:......|.|:   .:..:||:||.
 Worm   202 NVTLFGQSAGGACVDLLTLSPHSRDLFQKVVPMSGSAMCEFAMRTAENEAHVFDDILARLGFTGS 266

  Fly   289 NKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSW 353
            . .|...||:||:...:|...|.......        .|..:...|..:   ...:|.:.::...
 Worm   267 G-SKERLEFMRSLPCDKITGKTGYTYKQS--------GFMSLCPNYDGD---FFPKPLDELRKDA 319

  Fly   354 SHRIPMMFGGTSFEGLLF----------YPEVSR-------RPATLDEVGNCKNLLPSDLGLNLD 401
            |.|| :|.|....|||||          |.::.|       :...:|:|...:
 Worm   320 SKRI-LMTGIVGNEGLLFAFDRNTPYKDYTDLLRLKIEEDYKEDVVDDVEGIR------------ 371

  Fly   402 PKLRENYGLQLKKAYFGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHD 466
               :|.:....|....|||   :|.|.|..|... ...:|...||......:.....:||.||:
 Worm   372 ---KEIFEYYTKNISEGDE---EAIMRKAAEFVG-DSIFHTGVRATAQNAAEHGDEVWLYNFDY- 428

  Fly   467 SKLCNAIRIVLCGHQMRGV------CHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDVWTSFAA 525
               ||.....    .::|.      .||.:|.|:|...:..:..|...|.|::.....::.:||.
 Worm   429 ---CNPDGFA----PLKGYLPYIEPTHGMELRYLFGDGIISKFEPTEEELKMLDKFTTMFANFAK 486

  Fly   526 HGDPNCESIKSL--KFAP 541
            :|:|| |:..|.  ||.|
 Worm   487 YGNPN-ETGSSAWEKFDP 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	156/526 (30%)
cest-34	NP_001360105.1	COesterase	15..517	CDD:395084	161/538 (30%)