Protein Alignment alpha-Est10 and cest-35.2

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 163/546 - (29%)
• Similarity: 249/546 - (45%)
• Gaps: 91/546 - (16%)

  Fly    50 VIKTKSGPVRGVKRNTIWGGSYF--SFEKIPFAKPPVGDLRFKAPEAVEPWDQELDC-------- 104
            |.....||:||   |....|...  .:..|||||.|:||||||.....|.|.|.|||
 Worm    16 VFNASCGPIRG---NVYEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYKYGPGCP 77

  Fly   105 TSPADKPLQTHMFFRKYAGSEDCLYLNVYV---KDLQPDKLRPVMVWIYGGGYQVGEASRDMYSP 166
            .|.|...|............::||.|||:.   |..:.....||||:.||||::||.:|  |:.
 Worm    78 QSAALGALMVSQATNHDFAEDNCLNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVGFSS--MFD- 139

  Fly   167 DFFMS-----KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSN 226
            |:.::     |||::||..||:|.|||.:..|....  ||.||.||.:||:|||::|::||||.:
 Worm   140 DYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDVAR--GNWGLWDQALALQWVQKHIKSFGGDPS 202

  Fly   227 NITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRN--NWAYR-LAQKLGYTGD 288
            |:|:.|.||||||..||:|||.......|.|.|||:..||:....::  ...:| .|...||||
 Worm   203 NVTISGTSAGGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIRSKDVEGLIFREFANHHGYTG- 266

  Fly   289 NKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSW 353
            |..|::.::.:|......:||.........     :|:|.|     ..:.....|...||.:.
 Worm   267 NDSKSLLQWYQSQDSEIFLKAEGYKCPASG-----MFSFVP-----NFDGDFFPKPFDELRKE-- 319

  Fly   354 SHRIPMMFGGTSFEGLLF--YPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYGLQLKKA- 415
            :.::..:.....:|||.|  :....:.|         :.:|.:.||    |::..|....:|:|
 Worm   320 APKLGAIVSIGEYEGLGFEDFYAGQKTP---------QQMLSAALG----PEVVRNREEVVKRAA 371

  Fly   416 --YF---GDEPCNQANMMKFL-ELCSYREFWHPIYRAALNRVR---QSSAPTYLYRFDHDSKLCN 471
              |.   |:|  |:.|:.|.| |:  :.:::..:  .|.:.||   :.....|||.|::    .|
 Worm   372 ESYLKNGGNE--NEENIAKTLVEI--FGDYYFSV--GAFDTVRSLVKYGNTVYLYSFNY----FN 426

  Fly   472 AIRIVLCG--HQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDVW-TSFAAHGDPNCES 533
            ....::.|  .......||.||.|||    ...:...|.|.:.:..|:..: |:||.:|:||.:.
 Worm   427 PNTPIVFGKNRPFNAANHGSDLRYIF----GEGTGEFSKEDRQVMDMMGTYHTNFAKYGNPNGKG 487

  Fly   534 IKSLKFAPIENVTNFKCLNIGDQFEV 559
            :.    .|.|   .:...|.|..|::
 Worm   488 VS----VPWE---KYSLDNPGRYFKI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	158/527 (30%)
		Aes	<132..>279	CDD:223730	65/157 (41%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	163/546 (30%)
		Aes	<105..>239	CDD:223730	62/138 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157294
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.740