Protein Alignment alpha-Est10 and cest-32

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 156/547 - (28%)
• Similarity: 256/547 - (46%)
• Gaps: 95/547 - (17%)

  Fly    46 AIYSVIKTKSGPVRG-VKR--NTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSP 107
            |...|:....|||.| :.|  :.|..|    :..|||||.|:.:||||.|...|.|.:.|:|...
 Worm    12 ASLEVLNASCGPVIGNIYRHDDKIVNG----YLGIPFAKAPICELRFKKPVEAEKWTKPLNCHKY 72

  Fly   108 ADK-PLQTHMF-------FRKYAGSEDCLYLNVYVKDLQPDKL---RPVMVWIYGGGYQVGEASR 161
            ... |...||.       :|::| .::||.||::....:.::.   .|:||:.:|||:::|.:|
 Worm    73 GPGCPQSGHMISNLLPPGYREFA-EDNCLNLNIFAPSWKSEEFPNGLPIMVYFHGGGFEIGFSS- 135

  Fly   162 DMYSPDFFMS-----KDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAF 221
             |:. |:.:|     |||::||..||:|.|||::..|....  ||.||.||.:||:|||::|::|
 Worm   136 -MFD-DYSLSGTLPLKDVIVVTANYRVGPLGFMTTGDEVSR--GNYGLWDQTLALKWVQEHIKSF 196

  Fly   222 GGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNNWA--YR-LAQKL 283
            ||:.|.:|:.|.||||.|...|||||.:..|.|:.:.||||..|.::...:...|  :| .|:..
 Worm   197 GGNPNIVTVCGTSAGGVSAGLLALSPHSNKLFHRFMAMSGSAFCEFSIRTKEQEAEIFRNFAKHH 261

  Fly   284 GYTGDNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHEL 348
            ||.|::.: ::.|:.:|....:. :.|||.    ||.......|.|     ..:.....|...||
 Worm   262 GYEGEDSE-SLLEWYKSQPLSKF-QETATF----EKKASGFLTFIP-----NFDGDFFPKPFDEL 315

  Fly   349 MQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDL---GLNLDPKLRENYGL 410
            .:.  :.::..|.....:|||.|......|...:|.:   |:...||:   .:::..::.|.|..
 Worm   316 SRE--APKLDAMATVDEYEGLGFLTMFQSRRNDMDII---KSSFGSDVVENAVDVQKRIMEFYMK 375

  Fly   411 QLKKAYFGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSS---APTYLYRFDHDS----- 467
            .:      |:..::|...:.::|.|  :.|..|  .||..|:.|:   :..||..||:.:
 Worm   376 NI------DKNDDKAVEKRLIQLIS--DSWFNI--GALETVKTSTKYGSNAYLGSFDYYNMGSND 430

  Fly   468 --------KLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDVWTSFA 524
                    |..|               ||.:|.|:....:. :.:|...|.|||..|..:..:|.
 Worm   431 PYATWFPFKAAN---------------HGSELKYMLGEGMG-KFSPIEEEFKVIDMMGTLTANFV 479

  Fly   525 AHGDPNCESIKSL--KFAPIENVTNFK 549
            .:|:||..:...|  |:.|.:..:.||
 Worm   480 KYGNPNGINGPELWKKYTPEKPYSYFK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	150/524 (29%)
cest-32	NP_504397.1	COesterase	16..519	CDD:395084	155/543 (29%)