Protein Alignment alpha-Est10 and cest-4

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_501043.1
• Gene: cest-4 / 177445
• WormBaseID: WBGene00015930
• Length: 592
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 135/574 - (23%)
• Similarity: 226/574 - (39%)
• Gaps: 147/574 - (25%)

  Fly    49 SVIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPW--------------D 99
            :::.|..|.:.|.:.     ||:..|:.||.||||:|.|||:.||..|.|              .
 Worm    27 AIVSTSLGQIDGDQI-----GSFHLFKHIPLAKPPIGKLRFQKPEPPEKWTGVRNAKAYGPACIS 86

  Fly   100 QELDCTSPADKPLQTHMFFRKYAGSEDCLYLNVYVKD-LQPDKLRPVMVWIYGGG--YQVGEASR 161
            .....|||           :|:. .||||::|::..| ....|...|:.:.:|||  |.......
 Worm    87 NSSVSTSP-----------QKWI-DEDCLHINIFTSDKCLKSKDCAVVTYFHGGGLMYDSAVMFN 139

  Fly   162 DMYSPDFFMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSN 226
            |.|....|:::||:|...|:|||......::|..: .|.|..|.|.::.:.:|:..|..|||::.
 Worm   140 DTYLLGTFVNQDVIIAIPAFRLGIFSHFVVEDQSI-APTNLALYDILLGVEFVKNEIHNFGGNNQ 203

  Fly   227 NITLFGESAGGASTHFLALSPQTE---GLIHKAIVMSG----SVLCPWTQPPRNNWAYRLAQKLG 284
            ..|:.|.|.||:..:.|..|.:..   .|..::|.||.    ..|  ..|..:.|   |.|:..|
 Worm   204 KNTIMGHSYGGSIVNILTFSSKINHDLSLFQQSICMSSGHDFETL--EIQIQKTN---RFAKHAG 263

  Fly   285 ----------YTGDNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHT 339
                      .|....|....:.|::....|:::...  |..||.:.    .:|.:|:    ...
 Worm   264 CTVPSIIEKKMTTRQSDLYRMKCLQNKDALELLRVQR--LLEDEGYP----TYGYLVQ----REP 318

  Fly   340 VVAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKL 404
            ::.:.|::....| ..:|||:.|.|.:       |:...||            |..:|..|..:.
 Worm   319 LIQEIPYQEFMKS-PKKIPMLTGCTRY-------EMDHSPA------------PKPIGQALGFEN 363

  Fly   405 RENYGLQLKKAY------FG---DEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYL 460
            .|...::.:|.:      ||   ||  .||.|::              .|..:|.:...:.|.||
 Worm   364 PEEVYMKFRKDWDDEVYEFGNHSDE--TQAIMVQ--------------VRVRVNNLLSKNVPAYL 412

  Fly   461 YRFDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMV--DVWTSF 523
            |.:.:.                :...|.|||.|:   |..|:...|  |:::..|.|  .::.:|
 Worm   413 YEYTYP----------------KHARHTDDLFYL---MGVHRFEKD--ENEIELGKVYETIFMNF 456

  Fly   524 AAHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPEL-----QKIEPVW 572
            |..|||.    :..:.|..||.:.::....|:..|   .|::     :||...|
 Worm   457 AKFGDPK----EGFELANAENESYYEVYWDGETGE---RPQMKTKFEEKIINYW 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	127/537 (24%)
		Aes	<132..>279	CDD:223730	41/156 (26%)
cest-4	NP_501043.1	Abhydrolase	28..503	CDD:389770	134/571 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810