Protein Alignment alpha-Est10 and cest-5.1

DIOPT Version :9

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_501022.3
• Gene: cest-5.1 / 177429
• WormBaseID: WBGene00015279
• Length: 580
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 131/522 - (25%)
• Similarity: 210/522 - (40%)
• Gaps: 115/522 - (22%)

  Fly    50 VIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWD---QELD----CTSP 107
            :|.|..|.:.|.:.     |.|..|:||||||||||:|||:.|||...||   ..::    |.|.
 Worm    20 IIHTSFGHLEGAEI-----GDYHLFKKIPFAKPPVGNLRFQKPEAAGKWDGIRSAIEYGPACMSN 79

  Fly   108 ADKPLQTHMFFRKYAGSEDCLYLNVYV-KDLQPDKLRPVMVWIYGGG--YQVGEASRDMYSPDFF 169
            :.|......:.     .||||::|::. |.....:...:.|:|:|||  |.......|....|.|
 Worm    80 SSKTKSPQKWV-----DEDCLHVNIFTSKKCLKSRNCAIAVYIHGGGLTYDSAVMFNDTVLLDTF 139

  Fly   170 MSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGES 234
            :.:||::|...:|||.....::.:..: .|.|..|.|..:||.:|:..|.:|||:|..|||||.|
 Worm   140 VKRDVILVIPGFRLGIFSHFTVHNQNV-APNNLALYDITLALEFVKSEIHSFGGNSQKITLFGHS 203

  Fly   235 AGGASTHFLALSPQTE---GLIHKAIVMSGSV----LCPWTQPPRNNWAY-------RLAQKLGY 285
            .||.....:..|.:..   .|..:||||||..    |....:..:....|       :|.:|:
 Worm   204 YGGGLASMMTFSSEINRDLSLFQQAIVMSGGFYFEELKDHIEGTKRFVEYANCSVPLKLERKM-- 266

  Fly   286 TGDNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQP----- 345
            ....::..:.:.|:.:||.|:::.           .|:|...|     |.....|:.::|
 Worm   267 ERSQQEMYMMKCLQKLSGMELLRI-----------QRLLEDKG-----YPDFGGVILREPLFPDV 315

  Fly   346 --HELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRP----ATLDEVGNCKNLLPSDLGLNLDPKL 404
              .||:::  ...|||:.|.|:.|   |..|..:.|    ...:....|.....:|:...:
 Worm   316 KKFELLKS--PKNIPMLTGCTNLE---FDHESIKVPFGKYLEFENPDECDEKYRNDVESGV---- 371

  Fly   405 RENYGLQLKKAYFGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKL 469
             ||.|             |..:..:.:.|        |: :..:|.:.:::...|||.:.:..
 Worm   372 -ENRG-------------NHTDKTQGIIL--------PL-KLQINNLLENNVTAYLYEYTYPK-- 411

  Fly   470 CNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDVWTSFAAHGDPNCESI 534
                      |..    |.|||.||   |..|....|..|..:.....|:..:|...|:|.....
 Worm   412 ----------HGR----HTDDLSYI---MGVHAFEKDENEVHLEQVYKDMVINFIKLGEPGMGFE 459

  Fly   535 KS 536
            ||
 Worm   460 KS 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..542	CDD:278561	131/522 (25%)
		Aes	<132..>279	CDD:223730	46/163 (28%)
cest-5.1	NP_501022.3	Abhydrolase	19..495	CDD:389770	131/522 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156916
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740