Protein Alignment alpha-Est10 and cest-5.2

DIOPT Version :10

• Sequence 1: NP_001246962.1
• Gene: alpha-Est10 / 40896
• FlyBaseID: FBgn0015569
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 146/571 - (25%)
• Similarity: 228/571 - (39%)
• Gaps: 136/571 - (23%)

  Fly    33 VISFKYEQRKLSTAIY-SVIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVE 96
            :.||::        :| .:|||..|.:.|.:     .|.|..|.:|||||||:|.|||:.||:.|
 Worm    13 LFSFQF--------VYPRIIKTSLGRLEGKQ-----SGKYQLFRRIPFAKPPIGTLRFQKPESAE 64

  Fly    97 PWDQELDCT--SPADKPLQTHMFFRKYAGSEDCLYLNVYVKD-LQPDKLRPVMVWIYGGGYQVGE 158
            .|:...:.|  .||.....|.....:....||||::|::..| ....|...|:|:|:||  ::..
 Worm    65 KWNGVWNATEYGPACMSNSTWTQSPQKWVDEDCLHVNIFTSDKCLKSKDCAVVVYIHGG--EIVF 127

  Fly   159 ASRDMYSPDF----FMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIE 219
            .|..|::..|    |:.:||::|..|:|||.....::.|..: .|.|..|.|.|:|..:|:..|.
 Worm   128 DSAVMFNDTFLLESFVKQDVILVIPAFRLGIFSHFTVHDQNI-APNNLALYDIILAQEFVKSEIH 191

  Fly   220 AFGGDSNNITLFGESAGGASTHFLALSP---QTEGLIHKAIVMSGS----------------VLC 265
            .||||...|||||.|.||.....:|.|.   |...|..:.||||.:                |..
 Worm   192 NFGGDIQKITLFGHSYGGTIASMMAFSSEINQDLSLFQRIIVMSANQYFDTLEEQIERSDRVVKH 256

  Fly   266 PWTQPPRNNWAYRLAQKLGYTGDNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPV 330
            .....|.|     ||:|:..:  .|:|.:.:.|:.:||.|::....::..........|...||:
 Worm   257 AGCSVPTN-----LARKMNRS--QKEKYMMKCLQKLSGMELLSVQRSLEEAGYPDIGNLVLRGPL 314

  Fly   331 VEPYTTEHTVVAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSD 395
            ....|:         .|::::  ...|||:.|.|.||.           ...||.    :.:...
 Worm   315 FPDVTS---------LEMLES--PKMIPMLAGCTKFES-----------DDEDET----HFIGKH 353

  Fly   396 LGLNLDPKLRENYGLQLKKAYFGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYL 460
            .||....:..|.|...|:...|..:  |.::..:.:.:.:         :..::::|:...|.||
 Worm   354 FGLENPIECDEKYRKDLENGIFDRQ--NHSDKTQAIMVPT---------KLRVDQLRKHGVPAYL 407

  Fly   461 YRFDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPD-SPEH--KVITGMVDVWTS 522
            |.|.:.                :...|.|||.||   |..|....| :.||  ||...|:   .:
 Worm   408 YEFTYP----------------KHAFHTDDLYYI---MGIHPFEKDENEEHLEKVYRNML---IN 450

  Fly   523 FAAHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPELQKIEPVWN 573
            |...|:|                        |..||:..|.|....|..||
 Worm   451 FIKFGEP------------------------GMGFEMSDLNESTYFEIYWN 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Est10	NP_001246962.1	COesterase	49..533	CDD:395084	135/512 (26%)
cest-5.2	NP_501021.3	alpha/beta hydrolases	21..498	CDD:473884	143/555 (26%)